糖心Vlog

People

Dr Osama Mahmoud

Lecturer
School of Mathematics, Statistics and Actuarial Science (SMSAS)
Dr Osama Mahmoud

Profile

Biography

Dr Osama Mahmoud has joined the School of Mathematics, Statistics, and Actuarial Sciences as a Lecturer (Assistant Professor) in Data Science and Statistics in April 2020. Osama holds a PhD in Statistics from the 糖心Vlog. He is the Institutional Lead (IL) of the 糖心Vlog at the UK Reproducibility Network (UKRN), and had been an Honorary Senior Researcher in Medical Statistics at the University of Bristol Medical School from 2020 to 2024. Dr Osama is the first author of the Slope-Hunter method, a robust cutting-edge statistical method for bias correction in conditional genome-wide association studies, which has been published in the prestigious 'Nature Communications' journal in 2022. He is a Senior Fellow of the Higher Education Academy (SFHEA). Osama is the Director of the BSc Data Science and Analytics programme, and the Deputy Director of Research at the School of Mathematics, Statistics, and Actuarial Sciences. Osama has particular interests in Predictive Modelling, Health Data Science, Machine Learning, Bio and Medical Statistics, Data Visualisation, Causal Inference, and Explainable AI. Dr Osama has presented his research at several international conferences and workshops as an invited speaker and has published articles in reputable world-leading journals in the areas of methodological and applied Statistics, Machine Learning and Data Science. In 2020, Osama has launched a new module on programming and text analytics and co-developed a module on data visualisation and dynamic reporting. Osama has consistently obtained research funding to support his projects in Data Science and theoretical and applied Statistics. He has established strong collaborations with several international bodies and industrial partners such as United Nations Development Programme, Rolls Royce Motor Cars, and Recruitment Smart. Dr Osama has developed many Data Science and Statistical techniques, e.g., 'Proportion Overlapping Score' (POS), 'Slope-Hunter' (SH), and has authored several Data Science open-source tools that are available from the Comprehensive R Archive Network (CRAN) and his GitHub account. Osama has delivered a number of short courses for a wide range of audience in the areas of Machine Learning and Medical Statistics at national and international sites, including ICTP in Italy, EuADS in Luxumbourg, 糖心Vlog and University of Bristol in the UK. Osama is an active member in the British Data Science Society.

Appointments

糖心Vlog

  • Lecturer (Assistant Professor) in Data Science & Statistics, Department of Mathematical Sciences, 糖心Vlog (1/4/2020 - present)

Other academic

  • Honarary Senior Research Associate in Medical Statistics, Bristol Medical School, University of Bristol (1/4/2020 - present)

  • Senior Research Associate in Medical Statistics, School of Psychological Science, University of Bristol (1/1/2019 - 31/3/2020)

  • Senior Research Associate in Medical Statistics, MRC Integrative Epidemiology Unit (IEU), University of Bristol (1/1/2019 - 31/3/2020)

  • Senior Research Associate in Medical Statistics, Population Health Sciences, Bristol Medical school, University of Bristol (1/1/2017 - 31/12/2018)

  • Post-doctoral Research Associate in Statistics, NIHR Nutrition Biomedical Research Unit, University of Bristol (1/4/2015 - 31/12/2016)

Research and professional activities

Research interests

Medical Statistics and Genetic epidemiology

Key words: Genetic epidemiology
Open to supervise

Causal inference in public health

Key words: Genome wide association studies
Open to supervise

Data Science and Machine Learning

Key words: Classification
Open to supervise

Predictive modelling

Key words: Predictive modelling
Open to supervise

Current research

Machine Learning Methods for Precision Medicine

Improving predictive modelling via ensemble learning and feature reduction

Methods for collider bias correction in genome-wide association studies

Longitudinal studies of health-related outcomes

Analysing longitudinal data to gain insights into modifiable early-life risk factors of health-related outcomes, e.g. lung function, cardiovascular conditions, asthma.

Driving Value through AI Adoption in Assembly lines of Motor Cars manufacturing

Working with Rolls-Royce Motor Cars and Profusion Media Limited on driving values using AI with Assembly line data.

KTP Grant: Innovate UK/YU LIFE Ltd

Funding of 拢206,157: To evaluate and amplify the benefits to health and risk profile of customers who engage with the YuLife app using the latest modelling techniques and research from the public health and wellbeing domain.

Conferences and presentations

Explainable & Reproducible Data Science: Introduction to Data Visualisation and dynamic reporting

European Association for Data Science Summer School, Luxembourg, 1/6/2023

South-African Statistical Association pre-conference workshop

Invited presentation, 1/11/2022

Slope-Hunter: A robust method for collider bias correction in conditional genome-wide association studies

Invited presentation, Keynote presentation, International Bioinformatics Conference, IBC Morocco 2021, Tangier, Morocco, 27/12/2021

Publications

Journal articles (27)

Hayes, B., Fleming, L., Mahmoud, O., Martin, R., Lawlor, D., Robinson, T. and Richmond, R., (2025). . BMC Cancer. 25 (1), 357-

Granell, R., Haider, S., Deliu, M., Ullah, A., Mahmoud, O., Fontanella, S., Lowe, L., Simpson, A., Dodd, JW., Arshad, SH., Murray, CS., Roberts, G., Hughes, A., Park, C., Holloway, JW. and Custovic, A., (2024). . Thorax. 79 (8), 770-777

Mahmoud, O., Granell, R., Peralta, GP., Garcia-Aymerich, J., Jarvis, D., Henderson, J. and Sterne, J., (2023). . European Respiratory Journal. 61 (3), 2001316-2001316

Mahmoud, O., Dudbridge, F., Davey Smith, G., Munafo, M. and Tilling, K., (2022). . Nature Communications. 13 (1), 619-

Sillero-Rejon, C., Mahmoud, O., Tamayo, RM., Clavijo-Alvarez, AA., Adams, S. and Maynard, OM., (2022). . Addiction. 117 (6), 1737-1747

Cai, S., Hartley, A., Mahmoud, O., Tilling, K. and Dudbridge, F., (2022). . Genetic Epidemiology. 46 (5-6), 303-316

Talaei, M., Hughes, DA., Mahmoud, O., Emmett, PM., Granell, R., Guerra, S. and Shaheen, SO., (2021). . European Respiratory Journal. 58 (4), 2004407-2004407

Khan, Z., Gul, A., Perperoglou, A., Miftahuddin, M., Mahmoud, O., Adler, W. and Lausen, B., (2020). . Advances in Data Analysis and Classification. 14 (1), 97-116

Roda, C., Mahmoud, O., Peralta, GP., Fuertes, E., Granell, R., Serra, I., Henderson, J., Jarvis, D. and Garcia-Aymerich, J., (2020). . International Journal of Epidemiology. 49 (1), 131-141

Fuertes, E., Markevych, I., Thomas, R., Boyd, A., Granell, R., Mahmoud, O., Heinrich, J., Garcia-Aymerich, J., Roda, C., Henderson, J. and Jarvis, D., (2020). . Environment International. 140, 105749-105749

Yang, AS., Richard, BM., Wills, AK., Mahmoud, O., Sandy, JR. and Ness, AR., (2020). . Cleft Palate: Craniofacial Journal. 57 (1), 5-13

Peralta, GP., Fuertes, E., Granell, R., Mahmoud, O., Roda, C., Serra, I., Jarvis, D., Henderson, J. and Garcia-Aymerich, J., (2019). . American Journal of Respiratory and Critical Care Medicine. 200 (1), 75-83

Oksel, C., Granell, R., Mahmoud, O., Custovic, A., Henderson, AJ. and Breathing Together investigators, STELAR., (2019). . Allergy & clinical immunology international. 143 (5), 1783-1790.e11

Gul, A., Perperoglou, A., Khan, Z., Mahmoud, O., Miftahuddin, M., Adler, W. and Lausen, B., (2018). . Advances in Data Analysis and Classification. 12 (4), 827-840

Minelli, C., van der Plaat, DA., Leynaert, B., Granell, R., Amaral, AFS., Pereira, M., Mahmoud, O., Potts, J., Sheehan, NA., Bowden, J., Thompson, J., Jarvis, D., Davey Smith, G. and Henderson, J., (2018). . PLoS Medicine. 15 (8), e1002634-e1002634

Candler, TP., Mahmoud, O., Lynn, RM., Majbar, AA., Barrett, TG. and Shield, JPH., (2018). . Diabetic Medicine. 35 (6), 737-744

Mahmoud, O., Granell, R., Tilling, K., Minelli, C., Garcia-Aymerich, J., Holloway, JW., Custovic, A., Jarvis, D., Sterne, J. and Henderson, J., (2018). . American Journal of Respiratory and Critical Care Medicine. 198 (12), 1539-1548

Candler, TP., Mahmoud, O., Lynn, RM., Majbar, AA., Barrett, TG. and Shield, JPH., (2018). . Pediatric Diabetes. 19 (8), 1393-1399

Candler, T., Mahmoud, O., Edge, J. and Hamilton-Shield, J., (2017). . Diabetic Medicine. 34 (7), 983-986

Smallridge, J., Wills, AK., Mahmoud, O., Chong, A., Clark, V., Collard, M., Sandy, JR. and Ness, AR., (2017). . Orthodontics and Craniofacial Research. 20 (S2), 19-26

Hall, A., Wills, AK., Mahmoud, O., Sell, D., Waylen, A., Grewal, S., Sandy, JR. and Ness, AR., (2017). . Orthodontics and Craniofacial Research. 20 (S2), 8-18

Sell, D., Southby, L., Wren, Y., Wills, AK., Hall, A., Mahmoud, O., Waylen, A., Sandy, JR. and Ness, AR., (2017). . Orthodontics and Craniofacial Research. 20 (S2), 27-39

Broomfield, SJ., Mandavia, AK., Nicholson, JS., Mahmoud, O., King, AT., Rutherford, SA. and Ramsden, RT., (2017). . Otology and Neurotology. 38 (8), 1165-1173

Ness, AR., Wills, AK., Mahmoud, O., Hall, A., Sell, D., Smallridge, J., Southby, L., Stokes, D., Toms, S., Waylen, A., Wren, Y. and Sandy, JR., (2017). . Orthodontics and Craniofacial Research. 20 (S2), 48-51

Wills, AK., Mahmoud, O., Hall, A., Sell, D., Smallridge, J., Southby, L., Toms, S., Waylen, A., Wren, Y., Ness, AR. and Sandy, JR., (2017). . Orthodontics and Craniofacial Research. 20 (S2), 1-7

Waylen, A., Mahmoud, O., Wills, AK., Sell, D., Sandy, JR. and Ness, AR., (2017). . Orthodontics and Craniofacial Research. 20 (S2), 40-47

Mahmoud, O., Harrison, A., Perperoglou, A., Gul, A., Khan, Z., Metodiev, MV. and Lausen, B., (2014). . BMC Bioinformatics. 15 (1), 274-

Conferences (10)

Cai, S., Hartley, A., Mahmoud, O., Tilling, K. and Dudbridge, F., (2022). Genetic instrumental variables to adjust for collider bias

Granell, R., Haider, S., Deliu, M., Ullah, A., Mahmoud, O., Fontanella, S., Simpson, A., Turner, S., Arshad, SH., Murray, C., Roberts, G., Holloway, J. and Custovic, A., (2022). Trajectories of restrictive pattern of lung function FEV1/FVC to physiological peak and their relationship with early life risk-factors and cardiac markers

Fuertes, E., Markevych, I., Boyd, A., Mahmoud, O., Thomas, R., Heinrich, J., Garcia Aymerich, J., Roda, C., Henderson, J. and Jarvis, D., (2019). Lung function up to adolescence and residential greenspace

Minelli, C., Van Der Plaat, D., Leynaert, B., Granell, R., Amaral, AFS., Pereira, M., Mahmoud, O., Potts, J., Thompson, J., Jarvis, D., Davey-Smith, G. and Henderson, J., (2018). The effect of early puberty on asthma in women and men: A Mendelian randomization study

Mahmoud, O., Granell, R., Tilling, K., Minelli, C., Garcia-Aymerich, J., Holloway, J., Custovic, A., Jarvis, D., Sterne, J. and Henderson, J., (2018). Association of height growth in puberty with maximally attained lung function

Candler, T., Mahmoud, O., Lynn, R., Majbar, A., Barrett, T. and Shield, JPH., (2018). Treatment Adherence and Weight Loss Are Key Predictors of HbA1c One Year After Diagnosis of Childhood Type 2 Diabetes in UK

Mahmoud, O., Granell, R. and Henderson, AJ., (2018). S107鈥匨aternal and early-childhood risk factors on lung function in early adulthood

Mahmoud, O., Harrison, A., Gul, A., Khan, Z., Metodiev, MV. and Lausen, B., (2016).

Gul, A., Khan, Z., Perperoglou, A., Mahmoud, O., Miftahuddin, M., Adler, W. and Lausen, B., (2016).

Khan, Z., Gul, A., Mahmoud, O., Miftahuddin, M., Perperoglou, A., Adler, W. and Lausen, B., (2016).

Grants and funding

2023

To develop a new 'Job Discovery' Natural Language Processing (NLP) Chatbot which will help provide a superlative candidate advice and access to all potential opportunities when visiting the career page of an organisation.

Innovate UK (formerly Technology Strategy Board)

Yu Life Limited KTP 22_23 R4

Innovate UK (formerly Technology Strategy Board)

2021

Systematising Data Documentation: An automated framework for documenting health and bioscience data

糖心Vlog (GCRF)

Rolls Royce PhD studentship

Rolls Royce Motor Company

Optimising translation of an emotional face processing intervention for autistic children

University of Bristol (Funder)

Contact

o.mahmoud@essex.ac.uk
+44 (0) 1206 873025

Location:

3A.523, Colchester Campus

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