Dr Andrew Harrison

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Email
harry@essex.ac.uk -
Telephone
+44 (0) 1206 872964
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Location
STEM 5.10, Colchester Campus
Profile
Biography
I was originally an Astrophysicist, studying how stars formed. I developed an interest in whether life can be found on planets other than the Earth and so decided to broaden my knowledge by moving into the rapidly expanding field of bioinformatics. I am interested in applying mathematics and statistics towards all areas of scientific research. My research efforts are concentrated on the analysis of data-rich functional genomics experiments. These include microarrays and I collaborate with a number of biologists and medics.
Qualifications
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PhD in Astrophysics
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BSc in Physics with Astrophysics University of Manchester, (1991)
Appointments
糖心Vlog
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Senior Lecturer, Mathematical Sciences, 糖心Vlog (1/10/2004 - present)
Research and professional activities
Research interests
Bioinformatics
Teaching and supervision
Current teaching responsibilities
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Network Analysis (MA214)
Current supervision
Previous supervision

Degree subject: Statistics
Degree type: Doctor of Philosophy
Awarded date: 23/6/2022

Degree subject: Bio-Statistics
Degree type: Doctor of Philosophy
Awarded date: 26/1/2022

Degree subject: Statistics
Degree type: Doctor of Philosophy
Awarded date: 6/1/2021

Degree subject: Statistics
Degree type: Doctor of Philosophy
Awarded date: 24/5/2016

Degree subject: Bioinformatics
Degree type: Doctor of Philosophy
Awarded date: 2/3/2016

Degree subject: Statistics
Degree type: Doctor of Philosophy
Awarded date: 8/10/2015

Degree subject: Mathematics
Degree type: Master of Science (by Dissertation)
Awarded date: 22/9/2014

Degree subject: Bioinformatics
Degree type: Doctor of Philosophy
Awarded date: 6/1/2012
Publications
Journal articles (68)
Chathoth, K., Mikheeva, L., Crevel, G., Wolfe, J., Hunter, I., Beckett-Doyle, S., Cotterill, S., Dai, H., Harrison, A. and Zabet, N., (2022). . Genome Research. 32 (4), 682-698
Hu, X., Feng, C., Zhou, Y., Harrison, A. and Chen, M., (2022). . Bioinformatics. 28 (3), 694-702
Osuntoki, IG., Harrison, A., Dai, H., Bao, Y. and Zabet, NR., (2022). . Bioinformatics. 38 (14), btac387-btac387
Wang, X., Harrison, A., Chang, Y. and Liu, J., (2022). . Physics of Plasmas. 29 (7), 073506-073506
Wang, X. and Harrison, A., (2022). . Computational Biology and Chemistry. 101, 107782-107782
Woldegiorgis, ST., Wu, T., Gao, L., Huang, Y., Zheng, Y., Qiu, F., Xu, S., Tao, H., Harrison, A., Liu, W. and He, H., (2022). . Genes. 13 (8), 1353-1353
Wang, X. and Harrison, A., (2021). A general principle for spontaneous genetic symmetry breaking and pattern formation within cell populations. Journal of Theoretical Biology. 526, 110809-110809
Cannataro, M. and Harrison, A., (2021). . Briefings in Bioinformatics. 22 (2), 613-615
Ma, S., Song, Q., Tao, H., Harrison, A., Wang, S., Liu, W., Lin, S., Zhang, Z., Ai, Y. and He, H., (2019). Prediction of protein鈥損rotein interactions between fungus (Magnaporthe grisea) and rice (Oryza sativa L.). Briefings in Bioinformatics. 20 (2), 448-456
Tareke Woldegiorgis, S., Wang, S., He, Y., Xu, Z., Chen, L., Tao, H., Zhang, Y., Zou, Y., Harrison, A., Zhang, L., Ai, Y., Liu, W. and He, H., (2019). . Rice. 12 (1), 97-
Chen, M., Harrison, A., Shanahan, H. and Orlov, Y., (2017). . Journal of Integrative Bioinformatics. 14 (3), /j/jib.2017.14.issue-3/jib-2017-0052/jib-2017-0052-3/jib
Li, K., Xu, C., Huang, J., Liu, W., Zhang, L., Wan, W., Tao, H., Li, L., Lin, S., Harrison, A. and He, H., (2017). . Briefings in Bioinformatics. 18 (2), 270-278
Bai, Y., Dai, X., Harrison, A., Johnston, C. and Chen, M., (2016). . Briefings in Bioinformatics. 17 (1), 63-77
Alhaji, BB., Dai, H., Hayashi, Y., Vinciotti, V., Harrison, A. and Lausen, B., (2016). . Journal of Applied Statistics. 43 (8), 1369-1385
Wang, J., Meng, X., Yuan, C., Harrison, AP. and Chen, M., (2016). . Briefings in Functional Genomics. 15 (4), 278-287
Yuan, C., Wang, J., Harrison, AP., Meng, X., Chen, D. and Chen, M., (2015). . DNA Research. 22 (3), 233-243
Lin, S., Song, Q., Tao, H., Wang, W., Wan, W., Huang, J., Xu, C., Chebii, V., Kitony, J., Que, S., Harrison, A. and He, H., (2015). . Scientific Reports. 5 (1), 11940-
Corpas, M., Valdivia-Granda, W., Torres, N., Greshake, B., Coletta, A., Knaus, A., Harrison, AP., Cariaso, M., Moran, F., Nielsen, F., Swan, D., Weiss Sol铆s, DY., Krawitz, P., Schacherer, F., Schols, P., Yang, H., Borry, P., Glusman, G. and Robinson, PN., (2015). . BMC Genomics. 16 (1), 910-
Bai, Y., Dai, X., Harrison, AP. and Chen, M., (2015). . Briefings in Functional Genomics. 14 (2), 91-101
Shanahan, H., Harrison, AP. and Tobias May, S., (2015). . Advanced Techniques in Biology & Medicine. 03 (03)
Lin, S., Song, Q., Tao, H., Wang, W., Wan, W., Huang, J., Xu, C., Chebii, V., Kitony, J., Que, S., Harrison, AP. and He, H., (2015). Rice_Phospho 1.0: a new rice-specific SVM predictor for protein phosphorylation sites. Scientific Reports. 5, creators-Harrison=3AAndrew_P=3A=3A
Chen, D., Fu, L-Y., Zhang, Z., Li, G., Zhang, H., Jiang, L., Harrison, AP., Shanahan, HP., Klukas, C., Zhang, H-Y., Ruan, Y., Chen, L-L. and Chen, M., (2014). . Nucleic Acids Research. 42 (5), 3028-3043
Mahmoud, O., Harrison, A., Perperoglou, A., Gul, A., Khan, Z., Metodiev, MV. and Lausen, B., (2014). . BMC Bioinformatics. 15 (1), 274-
Musa, IK., Walker, SD., Owen, AM. and Harrison, AP., (2014). . Journal of Cloud Computing: Advances, Systems and Applications. 3 (1), 5-5
Shanahan, HP., Owen, AM. and Harrison, AP., (2014). . PLoS ONE. 9 (7), e102642-e102642
Musa, IK., Walker, S., Owen, AM. and Harrison, AP., (2014). Self-service infrastructure container for data intensive application. Journal of Cloud Computing: Advances, Systems and Applications. 3 (1), creators-Walker=3AStuart=3A=3A
Mahmoud, O., Harrison, AP., Perperoglou, A., Gul, A., Khan, Z., Metodiev, M. and Lausen, B., (2014). A feature selection method for classification within functional genomics experiments based on the proportional overlapping score. BMC Bioinformatics. 15 (1), creators-Lausen=3ABerthold=3A=3A
Peddada, SD., Shanahan, HP., Owen, AM. and Harrison, AP., (2014). Bioinformatics on the Cloud Computing Platform Azure. PloS One. 9 (7), creators-Harrison=3AAndrew_P=3A=3A
Harrison, A., Binder, H., Buhot, A., Burden, CJ., Carlon, E., Gibas, C., Gamble, LJ., Halperin, A., Hooyberghs, J., Kreil, DP., Levicky, R., Noble, PA., Ott, A., Pettitt, BM., Tautz, D. and Pozhitkov, AE., (2013). . Nucleic Acids Research. 41 (5), 2779-2796
Rizig, MA., McQuillin, A., Ng, A., Robinson, M., Harrison, A., Zvelebil, M., Hunt, SP. and Gurling, HM., (2012). A gene expression and systems pathway analysis of the effects of clozapine compared to haloperidol in the mouse brain implicates susceptibility genes for schizophrenia. Journal of Psychopharmacology. 26 (9), 1218-1230
Upton, GJG. and Harrison, AP., (2012). . Nucleic Acids Research. 40 (19), 9705-9716
Shanahan, HP., Memon, FN., Upton, GJG. and Harrison, AP., (2012). . Nucleic Acids Research. 40 (8), 3307-3315
Kheniche, A., Salhi, A., Harrison, A. and Dowden, JM., (2010). . Advances in Experimental Medicine and Biology. 680, 371-378
Memon, FN., Upton, GJG. and Harrison, AP., (2010). . Journal of Nucleic Acids. 2010 (1), 1-6
Rowsell, J., da Silva Camargo, R., Langdon, WB., Stalteri, MA. and Harrison, AP., (2010). . Journal of integrative bioinformatics. 7 (3)
Upton, GJG. and Harrison, AP., (2010). . Statistical Applications in Genetics and Molecular Biology. 9 (1), Article37-
Sanchez-Graillet, O., Stalteri, MA., Rowsell, J., Upton, GJG. and Harrison, AP., (2010). . Journal of integrative bioinformatics. 7 (2), 1662-1668
Memon, FN., Owen, AM., Sanchez-Graillet, O., Upton, GJG. and Harrison, AP., (2010). . Journal of integrative bioinformatics. 7 (2), 111-
Langdon, WB., Upton, GJG., da Silva Camargo, R. and Harrison, AP., (2010). . IEEE/ACM Transactions on Computational Biology and Bioinformatics. 7 (4), 647-653
Memon, FN., Owen, AM., Sanchez-Graillet, O., Upton, GJG. and Harrison, AP., (2010). Identifying the impact of G-Quadruplexes on Affymetrix 3' Arrays using Cloud Computing. Journal of Integrative Bioinformatics. 7(2) (111)
Rowsell, J., Camargo, RDS., Langdon, WB., Stalteri, MA. and Harrison, AP., (2010). Uncovering the expression patterns of chimeric transcripts using surveys of Affymetrix GeneChips. Journal of Integrative Bioinformatics. 7(3) (137)
Sanchez-Graillet, O., Stalteri, MA., Rowsell, J., Upton, GJG. and Harrison, AP., (2010). Using surveys of Affymetrix GeneChips to study antisense expression. Journal of integrative bioinformatics. 7(2) (114)
Upton, GJG. and Harrison, AP., (2010). The detection of blur in affymetrix GeneChips.. Statistical applications in genetics and molecular biology. 9 (1), creators-Harrison=3AAndrew_P=3A=3A
Langdon, WB. and Harrison, AP., (2009). . Algorithms for Molecular Biology. 4 (1), 6-
Upton, GJG., Sanchez-Graillet, O., Rowsell, J., Arteaga-Salas, JM., Graham, NS., Stalteri, MA., Memon, FN., May, ST. and Harrison, AP., (2009). . Briefings in Functional Genomics and Proteomics. 8 (3), 199-212
Langdon, WB., Upton, GJG. and Harrison, AP., (2009). . Briefings in Bioinformatics. 10 (3), 259-277
Langdon, WB. and Harrison, AP., (2008). . Soft Computing. 12 (12), 1169-1183
Sanchez-Graillet, O., Rowsell, J., Langdon, WB., Stalteri, M., Arteaga-Salas, JM., Upton, GJG. and Harrison, AP., (2008). . Journal of integrative bioinformatics. 5 (2), 298-305
Arteaga-Salas, JM., Zuzan, H., Langdon, WB., Upton, GJG. and Harrison, AP., (2008). . Briefings in Bioinformatics. 9 (1), 25-33
Upton, GJG., Langdon, WB. and Harrison, AP., (2008). . BMC Genomics. 9 (1), 613-
Chen, M. and Harrison, AP., (2008). . Genomics, Proteomics & Bioinformatics. 6 (3-4), 190-198
Arteaga-Salas, JM., Harrison, AP. and Upton, GJG., (2008). . Statistical Applications in Genetics and Molecular Biology. 7 (1), Article29-
Harrison, AP., Rowsell, J., Camargo, RDS., Langdon, WB., Stalteri, M., Upton, GJG. and Arteaga-Salas, JM., (2008). . Biochemical Society Transactions. 36 (3), 511-513
Upton, GJG., Langdon, WB. and Harrison, AP., (2008). G-spots cause incorrect expression measurement in Affymetrix microarrays. BMC Genomics. 9 (1), creators-Harrison=3AAndrew_P=3A=3A
Harrison, AP., Rowsell, J., Camargo, RDS., Langdon, WB., Stalteri, M., Upton, GJG. and Arteaga-Salas, JM., (2008). The use of Affymetrix GeneChips as a tool for studying alternative forms of RNA. Biochemical Society Transactions. 36 (Part 3), 511-513
Redfern, OC., Harrison, A., Dallman, T., Pearl, FMG. and Orengo, CA., (2007). CATHEDRAL: A Fast and Effective Algorithm to Predict Folds and Domain Boundaries from Multidomain Protein Structures. PLoS Computational Biology. 3 (11), e232-e232
Harrison, AP., Johnston, CE. and Orengo, CA., (2007). . BMC Bioinformatics. 8 (1), 195-
Stalteri, MA. and Harrison, AP., (2007). . BMC Bioinformatics. 8 (1), 13-
Harrison, AP., Johnston, CE. and Orengo, CA., (2007). Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips. BMC Bioinformatics. 8 (1), creators-Harrison=3AAndrew_P=3A=3A
Stalteri, MA. and Harrison, AP., (2007). Interpretation of multiple probe sets mapping to the same gene in Affymetrix GeneChips. BMC Bioinformatics. 8 (1), creators-Harrison=3AAndrew_P=3A=3A
Stalteri, M. and Harrison, A., (2006). Comparisons of Annotation Predictions for Affymetrix GeneChips??. Applied Bioinformatics. 5 (4), 237-248
Myers, RE., Gale, CV., Harrison, A., Takeuchi, Y. and Kellam, P., (2005). A statistical model for HIV-1 sequence classification using the subtype analyser (STAR). Bioinformatics. 21 (17), 3535-3540
Pearl, F., (2004). The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis. Nucleic Acids Research. 33 (Database issue), D247-D251
Harrison, A., Pearl, F., Sillitoe, I., Slidel, T., Mott, R., Thornton, J. and Orengo, C., (2003). Recognizing the fold of a protein structure. Bioinformatics. 19 (14), 1748-1759
Pearl, FMG., (2003). The CATH database: an extended protein family resource for structural and functional genomics. Nucleic Acids Research. 31 (1), 452-455
Harrison, A., Pearl, F., Mott, R., Thornton, J. and Orengo, C., (2002). Quantifying the Similarities within Fold Space. Journal of Molecular Biology. 323 (5), 909-926
Pearl, FMG., (2001). A rapid classification protocol for the CATH Domain Database to support structural genomics. Nucleic Acids Research. 29 (1), 223-227
Pearl, FMG., (2000). Assigning genomic sequences to CATH. Nucleic Acids Research. 28 (1), 277-282
Book chapters (1)
Harrison, A. and Shanahan, H., (2014). . In: Approaches in Integrative Bioinformatics. Springer Berlin Heidelberg. 21- 69. 9783642412806
Conferences (7)
Alhaji, BB., Dai, H., Hayashi, Y., Vinciotti, V., Harrison, A. and Lausen, B., (2016).
Mahmoud, O., Harrison, A., Gul, A., Khan, Z., Metodiev, MV. and Lausen, B., (2016).
Khuhro, ZUA. and Harrison, AP., (2010). A set of tolerance values for identifying shared motifs in RNA tertiary structures
Langdon, WB., Rowsell, J. and Harrison, AP., (2009). Creating regular expressions as mRNA motifs with GP to predict human exon splitting
Langdon, WB. and Harrison, AP., (2008).
Kheniche, A., Salhi, A., Harrison, A. and Dowden, JM., (2008).
Orengo, CA., Bray, JE., Buchan, DWA., Harrison, A., Lee, D., Pearl, FMG., Sillitoe, I., Todd, AE. and Thornton, JM., (2002). The CATH protein family database: A resource for structural and functional annotation of genomes
Reports and Papers (2)
Osuntoki, IG., Harrison, A., Dai, H., Bao, Y. and Zabet, NR., (2021). ZipHiC: a novel Bayesian framework to identify enriched interactions and experimental biases in Hi-C data
Langdon, WB. and Harrison, AP., (2008).
Grants and funding
2024
Effects of the Pandemic on ECC workforce resilience
糖心Vlog (ESRC IAA)
2011
Development of Bioinformatics Research...
British Council
Virtual Multidisciplinary EnviroNments using Cloud Infrastructures (Venus-C)
Royal Holloway & Bedford New College
2010
Chips, Computers & Crops SS10-015
Medical Research Council
2009
Chips, crops and computers
Biotechnology & Biology Science Res.Council
2008
China Partnering Award
Biotechnology & Biology Science Res.Council