糖心Vlog

People

Dr Andrew Harrison

Senior Lecturer
School of Mathematics, Statistics and Actuarial Science (SMSAS)
Dr Andrew Harrison
  • Email

  • Telephone

    +44 (0) 1206 872964

  • Location

    STEM 5.10, Colchester Campus

Profile

Biography

I was originally an Astrophysicist, studying how stars formed. I developed an interest in whether life can be found on planets other than the Earth and so decided to broaden my knowledge by moving into the rapidly expanding field of bioinformatics. I am interested in applying mathematics and statistics towards all areas of scientific research. My research efforts are concentrated on the analysis of data-rich functional genomics experiments. These include microarrays and I collaborate with a number of biologists and medics.

Qualifications

  • PhD in Astrophysics

  • BSc in Physics with Astrophysics University of Manchester, (1991)

Appointments

糖心Vlog

  • Senior Lecturer, Mathematical Sciences, 糖心Vlog (1/10/2004 - present)

Research and professional activities

Research interests

Bioinformatics

Open to supervise

Teaching and supervision

Current teaching responsibilities

  • Network Analysis (MA214)

Previous supervision

Liudmila Mikheeva
Liudmila Mikheeva
Thesis title: A Novel Statistical Framework to Detect Complex 3D Genome Organisation Patterns Into Topologically Associated Domains
Degree subject: Statistics
Degree type: Doctor of Philosophy
Awarded date: 23/6/2022
Itunu Godwin Osuntoki
Itunu Godwin Osuntoki
Thesis title: A Hidden Markov Random Field Based Bayesian Approach for the Detection of Chromatin Interactions in Hi-C Data
Degree subject: Bio-Statistics
Degree type: Doctor of Philosophy
Awarded date: 26/1/2022
Najlaa Tarik Jassim Jassim
Najlaa Tarik Jassim Jassim
Thesis title: Asymmetric Loss Functions and Combination of Forecasts with Applications in Equity Premium Prediction
Degree subject: Statistics
Degree type: Doctor of Philosophy
Awarded date: 6/1/2021
Baba Bukar Alhaji Bukar
Baba Bukar Alhaji Bukar
Thesis title: Bayesian Analysis for Mixtures of Discrete Distributions with a Non-Parametric Component
Degree subject: Statistics
Degree type: Doctor of Philosophy
Awarded date: 24/5/2016
Anne Margaret Owen
Anne Margaret Owen
Thesis title: Wide Scale Analysis of Transcriptomics Data Using Cloud Computing Methods
Degree subject: Bioinformatics
Degree type: Doctor of Philosophy
Awarded date: 2/3/2016
Osama Fathy Abdelhaleem Mahmoud
Osama Fathy Abdelhaleem Mahmoud
Thesis title: Improving Statistical Learning Within Functional Genomic Experiments By Means of Feature Selection
Degree subject: Statistics
Degree type: Doctor of Philosophy
Awarded date: 8/10/2015
James Christopher Waumsley
James Christopher Waumsley
Thesis title: An Analysis of Various Heuristic Approaches for Satisfying Routing Requests in Networks
Degree subject: Mathematics
Degree type: Master of Science (by Dissertation)
Awarded date: 22/9/2014
Farhat Naureen Memon
Farhat Naureen Memon
Thesis title: Study of the Effects Caused By the G-Quadruplex Structures on High-Throughput Nucleic Acid Measurements
Degree subject: Bioinformatics
Degree type: Doctor of Philosophy
Awarded date: 6/1/2012

Publications

Journal articles (68)

Chathoth, K., Mikheeva, L., Crevel, G., Wolfe, J., Hunter, I., Beckett-Doyle, S., Cotterill, S., Dai, H., Harrison, A. and Zabet, N., (2022). . Genome Research. 32 (4), 682-698

Hu, X., Feng, C., Zhou, Y., Harrison, A. and Chen, M., (2022). . Bioinformatics. 28 (3), 694-702

Osuntoki, IG., Harrison, A., Dai, H., Bao, Y. and Zabet, NR., (2022). . Bioinformatics. 38 (14), btac387-btac387

Wang, X., Harrison, A., Chang, Y. and Liu, J., (2022). . Physics of Plasmas. 29 (7), 073506-073506

Wang, X. and Harrison, A., (2022). . Computational Biology and Chemistry. 101, 107782-107782

Woldegiorgis, ST., Wu, T., Gao, L., Huang, Y., Zheng, Y., Qiu, F., Xu, S., Tao, H., Harrison, A., Liu, W. and He, H., (2022). . Genes. 13 (8), 1353-1353

Wang, X. and Harrison, A., (2021). A general principle for spontaneous genetic symmetry breaking and pattern formation within cell populations. Journal of Theoretical Biology. 526, 110809-110809

Cannataro, M. and Harrison, A., (2021). . Briefings in Bioinformatics. 22 (2), 613-615

Ma, S., Song, Q., Tao, H., Harrison, A., Wang, S., Liu, W., Lin, S., Zhang, Z., Ai, Y. and He, H., (2019). Prediction of protein鈥損rotein interactions between fungus (Magnaporthe grisea) and rice (Oryza sativa L.). Briefings in Bioinformatics. 20 (2), 448-456

Tareke Woldegiorgis, S., Wang, S., He, Y., Xu, Z., Chen, L., Tao, H., Zhang, Y., Zou, Y., Harrison, A., Zhang, L., Ai, Y., Liu, W. and He, H., (2019). . Rice. 12 (1), 97-

Chen, M., Harrison, A., Shanahan, H. and Orlov, Y., (2017). . Journal of Integrative Bioinformatics. 14 (3), /j/jib.2017.14.issue-3/jib-2017-0052/jib-2017-0052-3/jib

Li, K., Xu, C., Huang, J., Liu, W., Zhang, L., Wan, W., Tao, H., Li, L., Lin, S., Harrison, A. and He, H., (2017). . Briefings in Bioinformatics. 18 (2), 270-278

Bai, Y., Dai, X., Harrison, A., Johnston, C. and Chen, M., (2016). . Briefings in Bioinformatics. 17 (1), 63-77

Alhaji, BB., Dai, H., Hayashi, Y., Vinciotti, V., Harrison, A. and Lausen, B., (2016). . Journal of Applied Statistics. 43 (8), 1369-1385

Wang, J., Meng, X., Yuan, C., Harrison, AP. and Chen, M., (2016). . Briefings in Functional Genomics. 15 (4), 278-287

Yuan, C., Wang, J., Harrison, AP., Meng, X., Chen, D. and Chen, M., (2015). . DNA Research. 22 (3), 233-243

Lin, S., Song, Q., Tao, H., Wang, W., Wan, W., Huang, J., Xu, C., Chebii, V., Kitony, J., Que, S., Harrison, A. and He, H., (2015). . Scientific Reports. 5 (1), 11940-

Corpas, M., Valdivia-Granda, W., Torres, N., Greshake, B., Coletta, A., Knaus, A., Harrison, AP., Cariaso, M., Moran, F., Nielsen, F., Swan, D., Weiss Sol铆s, DY., Krawitz, P., Schacherer, F., Schols, P., Yang, H., Borry, P., Glusman, G. and Robinson, PN., (2015). . BMC Genomics. 16 (1), 910-

Bai, Y., Dai, X., Harrison, AP. and Chen, M., (2015). . Briefings in Functional Genomics. 14 (2), 91-101

Shanahan, H., Harrison, AP. and Tobias May, S., (2015). . Advanced Techniques in Biology & Medicine. 03 (03)

Lin, S., Song, Q., Tao, H., Wang, W., Wan, W., Huang, J., Xu, C., Chebii, V., Kitony, J., Que, S., Harrison, AP. and He, H., (2015). Rice_Phospho 1.0: a new rice-specific SVM predictor for protein phosphorylation sites. Scientific Reports. 5, creators-Harrison=3AAndrew_P=3A=3A

Chen, D., Fu, L-Y., Zhang, Z., Li, G., Zhang, H., Jiang, L., Harrison, AP., Shanahan, HP., Klukas, C., Zhang, H-Y., Ruan, Y., Chen, L-L. and Chen, M., (2014). . Nucleic Acids Research. 42 (5), 3028-3043

Mahmoud, O., Harrison, A., Perperoglou, A., Gul, A., Khan, Z., Metodiev, MV. and Lausen, B., (2014). . BMC Bioinformatics. 15 (1), 274-

Musa, IK., Walker, SD., Owen, AM. and Harrison, AP., (2014). . Journal of Cloud Computing: Advances, Systems and Applications. 3 (1), 5-5

Shanahan, HP., Owen, AM. and Harrison, AP., (2014). . PLoS ONE. 9 (7), e102642-e102642

Musa, IK., Walker, S., Owen, AM. and Harrison, AP., (2014). Self-service infrastructure container for data intensive application. Journal of Cloud Computing: Advances, Systems and Applications. 3 (1), creators-Walker=3AStuart=3A=3A

Mahmoud, O., Harrison, AP., Perperoglou, A., Gul, A., Khan, Z., Metodiev, M. and Lausen, B., (2014). A feature selection method for classification within functional genomics experiments based on the proportional overlapping score. BMC Bioinformatics. 15 (1), creators-Lausen=3ABerthold=3A=3A

Peddada, SD., Shanahan, HP., Owen, AM. and Harrison, AP., (2014). Bioinformatics on the Cloud Computing Platform Azure. PloS One. 9 (7), creators-Harrison=3AAndrew_P=3A=3A

Harrison, A., Binder, H., Buhot, A., Burden, CJ., Carlon, E., Gibas, C., Gamble, LJ., Halperin, A., Hooyberghs, J., Kreil, DP., Levicky, R., Noble, PA., Ott, A., Pettitt, BM., Tautz, D. and Pozhitkov, AE., (2013). . Nucleic Acids Research. 41 (5), 2779-2796

Rizig, MA., McQuillin, A., Ng, A., Robinson, M., Harrison, A., Zvelebil, M., Hunt, SP. and Gurling, HM., (2012). A gene expression and systems pathway analysis of the effects of clozapine compared to haloperidol in the mouse brain implicates susceptibility genes for schizophrenia. Journal of Psychopharmacology. 26 (9), 1218-1230

Upton, GJG. and Harrison, AP., (2012). . Nucleic Acids Research. 40 (19), 9705-9716

Shanahan, HP., Memon, FN., Upton, GJG. and Harrison, AP., (2012). . Nucleic Acids Research. 40 (8), 3307-3315

Kheniche, A., Salhi, A., Harrison, A. and Dowden, JM., (2010). . Advances in Experimental Medicine and Biology. 680, 371-378

Memon, FN., Upton, GJG. and Harrison, AP., (2010). . Journal of Nucleic Acids. 2010 (1), 1-6

Rowsell, J., da Silva Camargo, R., Langdon, WB., Stalteri, MA. and Harrison, AP., (2010). . Journal of integrative bioinformatics. 7 (3)

Upton, GJG. and Harrison, AP., (2010). . Statistical Applications in Genetics and Molecular Biology. 9 (1), Article37-

Sanchez-Graillet, O., Stalteri, MA., Rowsell, J., Upton, GJG. and Harrison, AP., (2010). . Journal of integrative bioinformatics. 7 (2), 1662-1668

Memon, FN., Owen, AM., Sanchez-Graillet, O., Upton, GJG. and Harrison, AP., (2010). . Journal of integrative bioinformatics. 7 (2), 111-

Langdon, WB., Upton, GJG., da Silva Camargo, R. and Harrison, AP., (2010). . IEEE/ACM Transactions on Computational Biology and Bioinformatics. 7 (4), 647-653

Memon, FN., Owen, AM., Sanchez-Graillet, O., Upton, GJG. and Harrison, AP., (2010). Identifying the impact of G-Quadruplexes on Affymetrix 3' Arrays using Cloud Computing. Journal of Integrative Bioinformatics. 7(2) (111)

Rowsell, J., Camargo, RDS., Langdon, WB., Stalteri, MA. and Harrison, AP., (2010). Uncovering the expression patterns of chimeric transcripts using surveys of Affymetrix GeneChips. Journal of Integrative Bioinformatics. 7(3) (137)

Sanchez-Graillet, O., Stalteri, MA., Rowsell, J., Upton, GJG. and Harrison, AP., (2010). Using surveys of Affymetrix GeneChips to study antisense expression. Journal of integrative bioinformatics. 7(2) (114)

Upton, GJG. and Harrison, AP., (2010). The detection of blur in affymetrix GeneChips.. Statistical applications in genetics and molecular biology. 9 (1), creators-Harrison=3AAndrew_P=3A=3A

Langdon, WB. and Harrison, AP., (2009). . Algorithms for Molecular Biology. 4 (1), 6-

Upton, GJG., Sanchez-Graillet, O., Rowsell, J., Arteaga-Salas, JM., Graham, NS., Stalteri, MA., Memon, FN., May, ST. and Harrison, AP., (2009). . Briefings in Functional Genomics and Proteomics. 8 (3), 199-212

Langdon, WB., Upton, GJG. and Harrison, AP., (2009). . Briefings in Bioinformatics. 10 (3), 259-277

Langdon, WB. and Harrison, AP., (2008). . Soft Computing. 12 (12), 1169-1183

Sanchez-Graillet, O., Rowsell, J., Langdon, WB., Stalteri, M., Arteaga-Salas, JM., Upton, GJG. and Harrison, AP., (2008). . Journal of integrative bioinformatics. 5 (2), 298-305

Arteaga-Salas, JM., Zuzan, H., Langdon, WB., Upton, GJG. and Harrison, AP., (2008). . Briefings in Bioinformatics. 9 (1), 25-33

Upton, GJG., Langdon, WB. and Harrison, AP., (2008). . BMC Genomics. 9 (1), 613-

Chen, M. and Harrison, AP., (2008). . Genomics, Proteomics & Bioinformatics. 6 (3-4), 190-198

Arteaga-Salas, JM., Harrison, AP. and Upton, GJG., (2008). . Statistical Applications in Genetics and Molecular Biology. 7 (1), Article29-

Harrison, AP., Rowsell, J., Camargo, RDS., Langdon, WB., Stalteri, M., Upton, GJG. and Arteaga-Salas, JM., (2008). . Biochemical Society Transactions. 36 (3), 511-513

Upton, GJG., Langdon, WB. and Harrison, AP., (2008). G-spots cause incorrect expression measurement in Affymetrix microarrays. BMC Genomics. 9 (1), creators-Harrison=3AAndrew_P=3A=3A

Harrison, AP., Rowsell, J., Camargo, RDS., Langdon, WB., Stalteri, M., Upton, GJG. and Arteaga-Salas, JM., (2008). The use of Affymetrix GeneChips as a tool for studying alternative forms of RNA. Biochemical Society Transactions. 36 (Part 3), 511-513

Redfern, OC., Harrison, A., Dallman, T., Pearl, FMG. and Orengo, CA., (2007). CATHEDRAL: A Fast and Effective Algorithm to Predict Folds and Domain Boundaries from Multidomain Protein Structures. PLoS Computational Biology. 3 (11), e232-e232

Harrison, AP., Johnston, CE. and Orengo, CA., (2007). . BMC Bioinformatics. 8 (1), 195-

Stalteri, MA. and Harrison, AP., (2007). . BMC Bioinformatics. 8 (1), 13-

Harrison, AP., Johnston, CE. and Orengo, CA., (2007). Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips. BMC Bioinformatics. 8 (1), creators-Harrison=3AAndrew_P=3A=3A

Stalteri, MA. and Harrison, AP., (2007). Interpretation of multiple probe sets mapping to the same gene in Affymetrix GeneChips. BMC Bioinformatics. 8 (1), creators-Harrison=3AAndrew_P=3A=3A

Stalteri, M. and Harrison, A., (2006). Comparisons of Annotation Predictions for Affymetrix GeneChips??. Applied Bioinformatics. 5 (4), 237-248

Myers, RE., Gale, CV., Harrison, A., Takeuchi, Y. and Kellam, P., (2005). A statistical model for HIV-1 sequence classification using the subtype analyser (STAR). Bioinformatics. 21 (17), 3535-3540

Pearl, F., (2004). The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis. Nucleic Acids Research. 33 (Database issue), D247-D251

Harrison, A., Pearl, F., Sillitoe, I., Slidel, T., Mott, R., Thornton, J. and Orengo, C., (2003). Recognizing the fold of a protein structure. Bioinformatics. 19 (14), 1748-1759

Pearl, FMG., (2003). The CATH database: an extended protein family resource for structural and functional genomics. Nucleic Acids Research. 31 (1), 452-455

Harrison, A., Pearl, F., Mott, R., Thornton, J. and Orengo, C., (2002). Quantifying the Similarities within Fold Space. Journal of Molecular Biology. 323 (5), 909-926

Pearl, FMG., (2001). A rapid classification protocol for the CATH Domain Database to support structural genomics. Nucleic Acids Research. 29 (1), 223-227

Pearl, FMG., (2000). Assigning genomic sequences to CATH. Nucleic Acids Research. 28 (1), 277-282

Book chapters (1)

Harrison, A. and Shanahan, H., (2014). . In: Approaches in Integrative Bioinformatics. Springer Berlin Heidelberg. 21- 69. 9783642412806

Conferences (7)

Alhaji, BB., Dai, H., Hayashi, Y., Vinciotti, V., Harrison, A. and Lausen, B., (2016).

Mahmoud, O., Harrison, A., Gul, A., Khan, Z., Metodiev, MV. and Lausen, B., (2016).

Khuhro, ZUA. and Harrison, AP., (2010). A set of tolerance values for identifying shared motifs in RNA tertiary structures

Langdon, WB., Rowsell, J. and Harrison, AP., (2009). Creating regular expressions as mRNA motifs with GP to predict human exon splitting

Langdon, WB. and Harrison, AP., (2008).

Kheniche, A., Salhi, A., Harrison, A. and Dowden, JM., (2008).

Orengo, CA., Bray, JE., Buchan, DWA., Harrison, A., Lee, D., Pearl, FMG., Sillitoe, I., Todd, AE. and Thornton, JM., (2002). The CATH protein family database: A resource for structural and functional annotation of genomes

Reports and Papers (2)

Osuntoki, IG., Harrison, A., Dai, H., Bao, Y. and Zabet, NR., (2021). ZipHiC: a novel Bayesian framework to identify enriched interactions and experimental biases in Hi-C data

Langdon, WB. and Harrison, AP., (2008).

Grants and funding

2024

Effects of the Pandemic on ECC workforce resilience

糖心Vlog (ESRC IAA)

2011

Development of Bioinformatics Research...

British Council

Virtual Multidisciplinary EnviroNments using Cloud Infrastructures (Venus-C)

Royal Holloway & Bedford New College

2010

Chips, Computers & Crops SS10-015

Medical Research Council

2009

Chips, crops and computers

Biotechnology & Biology Science Res.Council

2008

China Partnering Award

Biotechnology & Biology Science Res.Council

Contact

harry@essex.ac.uk
+44 (0) 1206 872964

Location:

STEM 5.10, Colchester Campus

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