糖心Vlog

People

Professor Leonard Schalkwyk

Professor
School of Life Sciences
Professor Leonard Schalkwyk

Profile

Biography

Originally a microbiologist from Canada, Leo studied at the University of Alberta, graduating in 1983. His PhD (Dalhousie University, 1991) was on genome mapping of Haloferax, an archaeon from the Dead Sea. He worked on genomic resources for several species and genome mapping of mouse in Hans Lehrach's laboratory at the Imperial Cancer Research Fund laboratory in London and at the Max-Planck-Institut für molekulare Genetik in Berlin. He was at the Social, Genetic and Developmental Psychiatry Research Centre, Kings College London from 2000-2014, where he worked on functional genomics and epigenomics, identifying genes involved in behaviour in the mouse and in depression, schizophrenia and Alzheimers disease in human. His research programme now includes epigenomics methods and environmental epigenomics as well as psychiatric epigenetics.

Qualifications

  • 1991 PhD in Biochemistry, Dalhousie University. Studies on the structure of the genome of Haloferax volcanii

  • 1983 BSc in Microbiology, University of Alberta

Appointments

糖心Vlog

  • Professor of Human Genetics, School of Biological Sciences, 糖心Vlog (1/10/2014 - present)

Other academic

  • Visiting Professor, SGDP, Institute of Psychiatry, Psychology and Neuroscience, King's College London (1/10/2014 - 30/9/2020)

  • Reader in Functional Genomics, SGDP, Institute of Psychiatry, King's College London (1/1/2004 - 30/9/2014)

  • Senior Lecturer in Molecular Genetics, SGDP, Institute of Psychiatry, King's College London (1/4/2000 - 31/12/2018)

Research and professional activities

Research interests

Genomic and epigenomic methods and software

Open to supervise

Epigenomics and the environment

Open to supervise

Alzheimers disease

Open to supervise

Schizophrenia

Open to supervise

Current research

DNA methylation profiles in human blood and brain, methods and software for epigenomic studies.

Conferences and presentations

Epigenetics Meets Social Neuroscience of Human Attachment

Keynote presentation, Organised one-day hybrid conference with about 100 participants, Colchester, United Kingdom, 5/7/2022

Functional Genomics and Epigenomics in Alzheimer鈥檚 disease

Invited presentation, Keynote presentation, ARUK East Network Scientific Meeting 2019, Cambridge, United Kingdom, 22/11/2019

Teaching and supervision

Previous supervision

Yucheng Wang
Yucheng Wang
Thesis title: Dna Methylation Analysis and Age Prediction
Degree subject: Computer Science
Degree type: Doctor of Philosophy
Awarded date: 30/6/2023
Olivia Alexandra Grant
Olivia Alexandra Grant
Thesis title: Influence of External Factors on the Human Epigenome
Degree subject: Biological Sciences
Degree type: Doctor of Philosophy
Awarded date: 15/5/2023
Alexandria Devon Andrayas
Alexandria Devon Andrayas
Thesis title: Epigenetic Biomarkers of Smoking, Inflammation, and Social Differences.
Degree subject: Biosocial Research
Degree type: Doctor of Philosophy
Awarded date: 22/11/2022
Tyler James Gorrie-Stone
Tyler James Gorrie-Stone
Thesis title: Dna Methylation: Methods and Analyses
Degree subject: Biochemistry
Degree type: Doctor of Philosophy
Awarded date: 8/10/2019
Alexandria Devon Andrayas
Alexandria Devon Andrayas
Thesis title: Considering the Impact of Smoking on Dna Methylation in Understanding Society
Degree subject: Biological Sciences
Degree type: Master of Science (by Dissertation)
Awarded date: 5/2/2018

Publications

Publications (2)

Grant, OA., Kumari, M., Schalkwyk, L. and Zabet, NR., (2024). Systematic investigation of interindividual variation of DNA methylation in human whole blood

Wang, Y., Grant, OA., Zhai, X., McDonald-Maier, KD. and Schalkwyk, LC., (2022). Recalibrating the cerebellum DNA methylation clock: implications for ageing rates comparison

Journal articles (181)

Dearman, A., Bao, Y., Schalkwyk, L. and Kumari, M., (2025). Serum proteomic correlates of mental health symptoms in a representative UK population sample. Brain, Behavior, & Immunity - Health. 44, 100947-100947

Hannon, E., Dempster, EL., Davies, JP., Chioza, B., Blake, GET., Burrage, J., Policicchio, S., Franklin, A., Walker, EM., Bamford, RA., Schalkwyk, LC. and Mill, J., (2024). Quantifying the proportion of different cell types in the human cortex using DNA methylation profiles. BMC Biology. 22 (1), 17-

Devall, M., Soanes, DM., Smith, AR., Dempster, EL., Smith, RG., Burrage, J., Iatrou, A., Hannon, E., Troakes, C., Moore, K., O'Neill, P., Al-Sarraj, S., Schalkwyk, L., Mill, J., Weedon, M. and Lunnon, K., (2023). . Frontiers in Endocrinology. 13, 1059120-

Wang, Y., Grant, O., Zhai, X., McDonald-Maier, K. and Schalkwyk, L., (2023). . GeroScience. 46 (1), 39-56

Vellame, DS., Shireby, G., MacCalman, A., Dempster, EL., Burrage, J., Gorrie-Stone, T., Schalkwyk, LS., Mill, J. and Hannon, E., (2023). . Epigenetics. 18 (1), 1217-1254

Flynn, R., Washer, S., Jeffries, AR., Andrayas, A., Shireby, G., Kumari, M., Schalkwyk, LC., Mill, J. and Hannon, E., (2022). . Human Molecular Genetics. 31 (18), 3181-3190

Wang, Y., Gorrie-Stone, TJ., Grant, OA., Andrayas, AD., Zhai, X., McDonald-Maier, KD. and Schalkwyk, LC., (2022). . Bioinformatics. 38 (16), 3950-3957

Grant, OA., Wang, Y., Kumari, M., Zabet, NR. and Schalkwyk, L., (2022). . Clinical Epigenetics. 14 (1), 62-

Bao, Y., Gorrie-Stone, T., Hannon, E., Hughes, A., Andrayas, A., Neilson, G., Burrage, J., Mill, J., Schalkwyk, L. and Kumari, M., (2022). . Scientific Reports. 12 (1), 22284-22284

Smith, RG., Pishva, E., Shireby, G., Smith, AR., Roubroeks, JAY., Hannon, E., Wheildon, G., Mastroeni, D., Gasparoni, G., Riemenschneider, M., Giese, A., Sharp, AJ., Schalkwyk, L., Haroutunian, V., Viechtbauer, W., van den Hove, DLA., Weedon, M., Brokaw, D., Francis, PT., Thomas, AJ., Love, S., Morgan, K., Walter, J., Coleman, PD., Bennett, DA., De Jager, PL., Mill, J. and Lunnon, K., (2021). . Nature Communications. 12 (1), 3517-

Min, JL., Hemani, G., Kumari, M., Schalkwyk, LC. and et al, (2021). . Nature Genetics. 53 (9), 1311-1321

Hannon, E., Dempster, EL., Mansell, G., Burrage, J., Bass, N., Bohlken, MM., Corvin, A., Curtis, CJ., Dempster, D., Di Forti, M., Dinan, TG., Donohoe, G., Gaughran, F., Gill, M., Gillespie, A., Gunasinghe, C., Hulshoff, HE., Hultman, CM., Johansson, V., Kahn, RS., Kaprio, J., Kenis, G., Kowalec, K., MacCabe, J., McDonald, C., McQuillin, A., Morris, DW., Murphy, KC., Mustard, CJ., Nenadic, I., O'Donovan, MC., Quattrone, D., Richards, AL., Rutten, BP., St Clair, D., Therman, S., Toulopoulou, T., Van Os, J., Waddington, JL., Wellcome Trust Case Control Consortium (WTCCC), CRESTAR consortium, Sullivan, P., Vassos, E., Breen, G., Collier, DA., Murray, RM., Schalkwyk, LS. and Mill, J., (2021). . eLife. 10, 1-53

Wang, Y., Hannon, E., Grant, O., Gorrie-Stone, T., Kumari, M., Mill, J., Zhai, X., McDonald-Maier, K. and Schalkwyk, L., (2021). . BMC Genomics. 22 (1), 484-

Leung, SK., Jeffries, AR., Castanho, I., Jordan, BT., Moore, K., Davies, JP., Dempster, EL., Bray, NJ., O'Neill, P., Tseng, E., Ahmed, Z., Collier, DA., Jeffery, ED., Prabhakar, S., Schalkwyk, L., Jops, C., Gandal, MJ., Sheynkman, GM., Hannon, E. and Mill, J., (2021). . Cell Reports. 37 (7), 110022-110022

脜senius, F., Gorrie-Stone, TJ., Brew, A., Panchbhaya, Y., Williamson, E., Schalkwyk, LC., Rakyan, VK., Holland, ML., Marzi, SJ. and Williams, DJ., (2020). . PLoS Genetics. 16 (10), e1009035-e1009035

Shireby, GL., Davies, JP., Francis, PT., Burrage, J., Walker, EM., Neilson, GWA., Dahir, A., Thomas, AJ., Love, S., Smith, RG., Lunnon, K., Kumari, M., Schalkwyk, LC., Morgan, K., Brookes, K., Hannon, E. and Mill, J., (2020). . Brain: a journal of neurology. 143 (12), 3763-3775

脜senius, F., Gorrie-Stone, TJ., Brew, A., Panchbaya, Y., Williamson, E., Schalkwyk, LC., Rakyan, VK., Holland, ML., Marzi, SJ. and Williams, DJ., (2020). DNA methylation covariation in human whole blood and sperm: implications for studies of intergenerational epigenetic effects

Gorrie-Stone, TJ., Smart, MC., Saffari, A., Malki, K., Hannon, E., Burrage, J., Mill, J., Kumari, M. and Schalkwyk, LC., (2019). . Bioinformatics. 35 (6), 981-986

Hannon, E., Marzi, SJ., Schalkwyk, LS. and Mill, J., (2019). . Molecular Brain. 12 (1), 7-

Hughes, A., Bao, Y., Smart, M., Gorrie-Stone, T., Hannon, E., Mill, J., Burrage, J., Schalkwyk, L. and Kumari, M., (2019). THE AUTHORS REPLY. American Journal of Epidemiology. 188 (2), 488-489

Mansell, G., Gorrie-Stone, TJ., Bao, Y., Kumari, M., Schalkwyk, LS., Mill, J. and Hannon, E., (2019). . BMC Genomics. 20 (1), 366-

Wong, CCY., Smith, RG., Hannon, E., Ramaswami, G., Parikshak, NN., Assary, E., Troakes, C., Poschmann, J., Schalkwyk, LC., Sun, W., Prabhakar, S., Geschwind, DH. and Mill, J., (2019). . Human Molecular Genetics. 28 (13), 2201-2211

Bell, CG., Lowe, R., Adams, PD., Baccarelli, AA., Beck, S., Bell, JT., Christensen, BC., Gladyshev, VN., Heijmans, BT., Horvath, S., Ideker, T., Issa, J-PJ., Kelsey, KT., Marioni, RE., Reik, W., Relton, CL., Schalkwyk, LC., Teschendorff, AE., Wagner, W., Zhang, K. and Rakyan, VK., (2019). . Genome Biology. 20 (1), 249-

El Khoury, LY., Gorrie-Stone, TJ., Smart, M., Hughes, A., Bao, Y., Andrayas, A., Burrage, J., Hannon, E., Kumari, M., Mill, J. and Schalkwyk, L., (2019). . Genome Biology. 20 (1), 283-

Saffari, A., Arno, M., Nasser, E., Ronald, A., Wong, CCY., Schalkwyk, LC., Mill, J., Dudbridge, F. and Meaburn, EL., (2019). . Molecular Autism. 10 (1), 38-38

Rutten, BPF., Vermetten, E., Vinkers, CH., Ursini, G., Daskalakis, NP., Pishva, E., de Nijs, L., Houtepen, LC., Eijssen, L., Jaffe, AE., Kenis, G., Viechtbauer, W., van den Hove, D., Schraut, KG., Lesch, K-P., Kleinman, JE., Hyde, TM., Weinberger, DR., Schalkwyk, L., Lunnon, K., Mill, J., Cohen, H., Yehuda, R., Baker, DG., Maihofer, AX., Nievergelt, CM., Geuze, E. and Boks, MPM., (2018). . Molecular Psychiatry. 23 (5), 1145-1156

Smith, RG., Hannon, E., De Jager, PL., Chibnik, L., Lott, SJ., Condliffe, D., Smith, AR., Haroutunian, V., Troakes, C., Al-Sarraj, S., Bennett, DA., Powell, J., Lovestone, S., Schalkwyk, L., Mill, J. and Lunnon, K., (2018). . Alzheimer's and Dementia. 14 (12), 1580-1588

Hughes, A., Smart, M., Gorrie-Stone, T., Hannon, E., Mill, J., Bao, Y., Burrage, J., Schalkwyk, L. and Kumari, M., (2018). . American Journal of Epidemiology. 187 (11), 2346-2354

Hannon, E., Gorrie-Stone, TJ., Smart, MC., Burrage, J., Hughes, A., Bao, Y., Kumari, M., Schalkwyk, LC. and Mill, J., (2018). . The American Journal of Human Genetics. 103 (5), 654-665

Marzi, SJ., Leung, SK., Ribarska, T., Hannon, E., Smith, AR., Pishva, E., Poschmann, J., Moore, K., Troakes, C., Al-Sarraj, S., Beck, S., Newman, S., Lunnon, K., Schalkwyk, LC. and Mill, J., (2018). . Nature Neuroscience. 21 (11), 1618-1627

O鈥橞rien, HE., Hannon, E., Hill, MJ., Toste, CC., Robertson, MJ., Morgan, JE., McLaughlin, G., Lewis, CM., Schalkwyk, LC., Hall, LS., Pardi帽as, AF., Owen, MJ., O鈥橠onovan, MC., Mill, J. and Bray, NJ., (2018). . Genome Biology. 19 (1), 194-

Viana, J., Hannon, E., Dempster, E., Pidsley, R., Macdonald, R., Knox, O., Spiers, H., Troakes, C., Al-Saraj, S., Turecki, G., Schalkwyk, LC. and Mill, J., (2017). . Human Molecular Genetics. 26 (1), 210-225

Malki, K., Tosto, MG., Mouri帽o鈥怲al铆n, H., Rodr铆guez鈥怢orenzo, S., Pain, O., Jumhaboy, I., Liu, T., Parpas, P., Newman, S., Malykh, A., Carboni, L., Uher, R., McGuffin, P., Schalkwyk, LC., Bryson, K. and Herbster, M., (2017). . American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 174 (3), 235-250

Janecka, M., Marzi, SJ., Parsons, MJ., Liu, L., Paya-Cano, JL., Smith, RG., Fernandes, C. and Schalkwyk, LC., (2017). . Scientific Reports. 7 (1), 41204-

Janecka, M., Mill, J., Basson, MA., Goriely, A., Spiers, H., Reichenberg, A., Schalkwyk, LC. and Fernandes, C., (2017). . Translational Psychiatry. 7 (1), e1019-e1019

Janecka, M., Haworth, CMA., Ronald, A., Krapohl, E., Happ茅, F., Mill, J., Schalkwyk, LC., Fernandes, C., Reichenberg, A. and Rijsdijk, F., (2017). . Journal of the American Academy of Child & Adolescent Psychiatry. 56 (5), 383-390

Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, EB., Devall, M., Soininen, H., K艂oszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, AN., Powell, J., Lovestone, S. and Hodges, A., (2017). . Neurobiology of Aging. 53, 36-47

Devall, M., Smith, RG., Jeffries, A., Hannon, E., Davies, MN., Schalkwyk, L., Mill, J., Weedon, M. and Lunnon, K., (2017). . Clinical Epigenetics. 9 (1), 47-

Spiers, H., Hannon, E., Schalkwyk, LC., Bray, NJ. and Mill, J., (2017). . BMC Genomics. 18 (1), 738-

Smith, AR., Smith, RG., Condliffe, D., Hannon, E., Schalkwyk, L., Mill, J. and Lunnon, K., (2016). . Neurobiology of Aging. 47, 35-40

Hannon, E., Dempster, E., Viana, J., Burrage, J., Smith, AR., Macdonald, R., St Clair, D., Mustard, C., Breen, G., Therman, S., Kaprio, J., Toulopoulou, T., Pol, HEH., Bohlken, MM., Kahn, RS., Nenadic, I., Hultman, CM., Murray, RM., Collier, DA., Bass, N., Gurling, H., McQuillin, A., Schalkwyk, L. and Mill, J., (2016). . Genome Biology. 17 (1), 176-

Lunnon, K., Hannon, E., Smith, RG., Dempster, E., Wong, C., Burrage, J., Troakes, C., Al-Sarraj, S., Kepa, A., Schalkwyk, L. and Mill, J., (2016). . Genome Biology. 17 (1), 27-

Carter, KW., Carter, KW., Francis, RW., Bresnahan, M., Gissler, M., Gr酶nborg, TK., Gross, R., Gunnes, N., Hammond, G., Hornig, M., Hultman, CM., Huttunen, J., Langridge, A., Leonard, H., Newman, S., Parner, ET., Petersson, G., Reichenberg, A., Sandin, S., Schendel, DE., Schalkwyk, L., Sourander, A., Steadman, C., Stoltenberg, C., Suominen, A., Sur茅n, P., Susser, E., Sylvester Vethanayagam, A. and Yusof, Z., (2016). . International Journal of Epidemiology. 45 (2), 408-416

Malki, K., Du Rietz, E., Crusio, WE., Pain, O., Paya鈥怌ano, J., Karadaghi, RL., Sluyter, F., de Boer, SF., Sandnabba, K., Schalkwyk, LC., Asherson, P. and Tosto, MG., (2016). . American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171 (6), 827-838

Houtepen, LC., Vinkers, CH., Carrillo-Roa, T., Hiemstra, M., Van Lier, PA., Meeus, W., Branje, S., Heim, CM., Nemeroff, CB., Mill, J., Schalkwyk, LC., Creyghton, MP., Kahn, RS., Jo毛ls, M., Binder, EB. and Boks, MPM., (2016). . Nature Communications. 7 (1), creators-Schalkwyk=3ALeonard_C=3A=3A

Hannon, E., Spiers, H., Viana, J., Pidsley, R., Burrage, J., Murphy, TM., Troakes, C., Turecki, G., O'Donovan, MC., Schalkwyk, LC., Bray, NJ. and Mill, J., (2016). . Nature Neuroscience. 19 (1), 48-54

Malki, K., Tosto, MG., Pain, O., Sluyter, F., Mineur, YS., Crusio, WE., de Boer, S., Sandnabba, KN., Kesserwani, J., Robinson, E., Schalkwyk, LC. and Asherson, P., (2016). . American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 171 (3), 427-436

Marzi, SJ., Meaburn, EL., Dempster, EL., Lunnon, K., Paya-Cano, JL., Smith, RG., Volta, M., Troakes, C., Schalkwyk, LC. and Mill, J., (2016). . Epigenetics. 11 (1), 24-35

Hannon, E., Lunnon, K., Schalkwyk, L. and Mill, J., (2015). . Epigenetics. 10 (11), 1024-1032

Elliott, G., Hong, C., Xing, X., Zhou, X., Li, D., Coarfa, C., Bell, RJA., Maire, CL., Ligon, KL., Sigaroudinia, M., Gascard, P., Tlsty, TD., Harris, RA., Schalkwyk, LC., Bilenky, M., Mill, J., Farnham, PJ., Kellis, M., Marra, MA., Milosavljevic, A., Hirst, M., Stormo, GD., Wang, T. and Costello, JF., (2015). . Nature Communications. 6 (1), creators-Schalkwyk=3ALeonard_C=3A=3A

Janecka, M., Manduca, A., Servadio, M., Trezza, V., Smith, R., Mill, J., Schalkwyk, LC., Reichenberg, A. and Fernandes, C., (2015). . Genes, Brain and Behavior. 14 (6), 443-453

Malki, K., Pain, O., Tosto, MG., Du Rietz, E., Carboni, L. and Schalkwyk, LC., (2015). . Translational Psychiatry. 5 (3), e519-e519

Martin, C., Tansey, KE., Schalkwyk, LC. and Powell, TR., (2015). . Biomarkers in Medicine. 9 (2), 169-180

Malki, K., Mineur, YS., Tosto, MG., Campbell, J., Karia, P., Jumabhoy, I., Sluyter, F., Crusio, WE. and Schalkwyk, LC., (2015). . BMC Genomics. 16 (1), 262-

Spiers, H., Hannon, E., Schalkwyk, LC., Smith, R., Wong, CCY., O鈥橠onovan, MC., Bray, NJ. and Mill, J., (2015). . Genome Research. 25 (3), 338-352

Boks, MP., Mierlo, HCV., Rutten, BPF., Radstake, TRDJ., De Witte, L., Geuze, E., Horvath, S., Schalkwyk, LC., Vinkers, CH., Broen, JCA. and Vermetten, E., (2015). . Psychoneuroendocrinology. 51, 506-512

Ilott, NE., Schneider, T., Mill, J., Schalkwyk, L., Brolese, G., Bizarro, L., Stolerman, IP., Dempster, E. and Asherson, P., (2014). . PLoS ONE. 9 (2), creators-Schalkwyk=3ALeonard_C=3A=3A

Condliffe, D., Wong, A., Troakes, C., Proitsi, P., Patel, Y., Chouliaras, L., Fernandes, C., Cooper, J., Lovestone, S., Schalkwyk, L., Mill, J. and Lunnon, K., (2014). . Neurobiology of Aging. 35 (8), 1850-1854

Viana, J., Pidsley, R., Troakes, C., Spiers, H., Wong, CCY., Al-Sarraj, S., Craig, I., Schalkwyk, L. and Mill, J., (2014). . Epigenetics. 9 (4), 587-599

Bell, JT., Loomis, AK., Butcher, LM., Gao, F., Zhang, B., Hyde, CL., Sun, J., Wu, H., Ward, K., Harris, J., Scollen, S., Davies, MN., Schalkwyk, LC., Mill, J., Williams, FMK., Li, N., Deloukas, P., Beck, S., McMahon, SB., Wang, J., John, SL. and Spector, TD., (2014). . Nature Communications. 5 (1), 2978-

Wong, CCY., Meaburn, EL., Ronald, A., Price, TS., Jeffries, AR., Schalkwyk, LC., Plomin, R. and Mill, J., (2014). . Molecular Psychiatry. 19 (4), 495-503

Pidsley, R., Viana, J., Hannon, E., Spiers, H., Troakes, C., Al-saraj, S., Mechawar, N., Turecki, G., Schalkwyk, LC., Bray, NJ. and Mill, J., (2014). . Genome Biology. 15 (10), creators-Schalkwyk=3ALeonard_C=3A=3A

Malki, K., Pain, O., Du Rietz, E., Tosto, MG., Paya-Cano, J., Sandnabba, KN., de Boer, S., Schalkwyk, LC. and Sluyter, F., (2014). . neurogenetics. 15 (4), 255-266

Powell, TR., McGuffin, P., D'Souza, UM., Cohen-Woods, S., Hosang, GM., Martin, C., Matthews, K., Day, RK., Farmer, AE., Tansey, KE. and Schalkwyk, LC., (2014). . PLoS ONE. 9 (3), creators-Schalkwyk=3ALeonard_C=3A=3A

Tarantino, LM. and Schalkwyk, LC., (2014). . Mammalian Genome. 25 (1-2), 1-2

Powell, TR., Powell鈥怱mith, G., Haddley, K., Mcguffin, P., Quinn, J., Schalkwyk, LC., Farmer, AE. and D'Souza, UM., (2014). . International Journal of Methods in Psychiatric Research. 23 (2), 279-288

Malki, K., Keers, R., Tosto, MG., Lourdusamy, A., Carboni, L., Domenici, E., Uher, R., McGuffin, P. and Schalkwyk, LC., (2014). . BMC Medicine. 12 (1), 73-

Smith, RG., Fernandes, C., Kember, R., Schalkwyk, LC., Buxbaum, J., Reichenberg, A. and Mill, J., (2014). . Molecular Autism. 5 (1), creators-Schalkwyk=3ALeonard_C=3A=3A

Lunnon, K., Smith, R., Hannon, E., De Jager, PL., Srivastava, G., Volta, M., Troakes, C., Al-Sarraj, S., Burrage, J., Macdonald, R., Condliffe, D., Harries, LW., Katsel, P., Haroutunian, V., Kaminsky, Z., Joachim, C., Powell, J., Lovestone, S., Bennett, DA., Schalkwyk, LC. and Mill, J., (2014). . Nature Neuroscience. 17 (9), 1164-1170

Punapart, M., Eltermaa, M., Oflijan, J., S眉tt, S., Must, A., K玫ks, S., Schalkwyk, LC., Fernandes, C., Vasar, E., Soomets, U. and Terasmaa, A., (2014). . PPAR Research. 2014, 1-11

De Jager, PL., Srivastava, G., Lunnon, K., Burgess, J., Schalkwyk, LC., Yu, L., Eaton, ML., Keenan, BT., Ernst, J., McCabe, C., Tang, A., Raj, T., Replogle, J., Brodeur, W., Gabriel, S., Chai, HS., Younkin, C., Younkin, SG., Zou, F., Szyf, M., Epstein, CB., Schneider, JA., Bernstein, BE., Meissner, A., Ertekin-Taner, N., Chibnik, LB., Kellis, M., Mill, J. and Bennett, DA., (2014). . Nature Neuroscience. 17 (9), 1156-1163

Davis, OSP., Band, G., Pirinen, M., Haworth, CMA., Meaburn, EL., Kovas, Y., Harlaar, N., Docherty, SJ., Hanscombe, KB., Trzaskowski, M., Curtis, CJC., Strange, A., Freeman, C., Bellenguez, C., Su, Z., Pearson, R., Vukcevic, D., Langford, C., Deloukas, P., Hunt, S., Gray, E., Dronov, S., Potter, SC., Tashakkori-Ghanbaria, A., Edkins, S., Bumpstead, SJ., Blackwell, JM., Bramon, E., Brown, MA., Casas, JP., Corvin, A., Duncanson, A., Jankowski, JAZ., Markus, HS., Mathew, CG., Palmer, CNA., Rautanen, A., Sawcer, SJ., Trembath, RC., Viswanathan, AC., Wood, NW., Barroso, I., Peltonen, L., Dale, PS., Petrill, SA., Schalkwyk, LS., Craig, IW., Lewis, CM., Price, TS., Donnelly, P., Plomin, R. and Spencer, CCA., (2014). . Nature Communications. 5 (1), creators-Schalkwyk=3ALeonard_C=3A=3A

Smith, RG., Reichenberg, A., Kember, RL., Buxbaum, JD., Schalkwyk, LC., Fernandes, C. and Mill, J., (2013). . Molecular Psychiatry. 18 (6), 635-636

Powell, TR., Smith, RG., Hackinger, S., Schalkwyk, LC., Uher, R., McGuffin, P., Mill, J. and Tansey, KE., (2013). . Translational Psychiatry. 3 (9), e300-e300

Powell, TR., Tansey, KE., Breen, G., Farmer, AE., Craig, IW., Uher, R., McGuffin, P., D鈥橲ouza, UM. and Schalkwyk, LC., (2013). . Journal of Psychopharmacology. 27 (7), 609-615

Pidsley, R., Wong, CCY., Volta, M., Lunnon, K., Mill, J. and Schalkwyk, LC., (2013). . BMC Genomics. 14 (1), 293-

Powell, TR., Schalkwyk, LC., Heffernan, AL., Breen, G., Lawrence, T., Price, T., Farmer, AE., Aitchison, KJ., Craig, IW., Danese, A., Lewis, C., McGuffin, P., Uher, R., Tansey, KE. and D'Souza, UM., (2013). . European Neuropsychopharmacology. 23 (9), 1105-1114

Navarrete, K., Pedroso, I., De Jong, S., Stefansson, H., Steinberg, S., Stefansson, K., Ophoff, RA., Schalkwyk, LC. and Collier, DA., (2013). . American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 162 (1), 1-16

Malki, K., Tosto, MG., Jumabhoy, I., Lourdusamy, A., Sluyter, F., Craig, I., Uher, R., McGuffin, P. and Schalkwyk, LC., (2013). . Pharmacogenomics. 14 (16), 1979-1990

Lill, M., K玫ks, S., Soomets, U., Schalkwyk, LC., Fernandes, C., Lutsar, I. and Taba, P., (2013). . Frontiers in Neuroscience. 7 (7), 33-

K玫ks, S., Overall, RW., Ivask, M., Soomets, U., Guha, M., Vasar, E., Fernandes, C. and Schalkwyk, LC., (2013). . Physiological Genomics. 45 (5), 182-190

Kember, RL., Dempster, EL., Lee, THA., Schalkwyk, LC., Mill, J. and Fernandes, C., (2012). . Brain and Behavior. 2 (4), 455-467

Pidsley, R., Fernandes, C., Viana, J., Paya-Cano, JL., Liu, L., Smith, RG., Schalkwyk, LC. and Mill, J., (2012). . Molecular Brain. 5 (1), 42-

Davies, MN., Volta, M., Pidsley, R., Lunnon, K., Dixit, A., Lovestone, S., Coarfa, C., Harris, RA., Milosavljevic, A., Troakes, C., Al-Sarraj, S., Dobson, R., Schalkwyk, LC. and Mill, J., (2012). . Genome Biology. 13 (6), R43-

Jeffries, AR., Perfect, LW., Ledderose, J., Schalkwyk, LC., Bray, NJ., Mill, J. and Price, J., (2012). . Stem Cells. 30 (9), 1938-1947

Parsons, MJ., Grimm, C., Paya-Cano, J., Fernandes, C., Liu, L., Philip, VM., Chesler, EJ., Nietfeld, W., Lehrach, H. and Schalkwyk, LC., (2012). . BMC Genomics. 13 (1), 476-

Keers, R., Pedroso, I., Breen, G., Aitchison, KJ., Nolan, PM., Cichon, S., N枚then, MM., Rietschel, M., Schalkwyk, LC. and Fernandes, C., (2012). . PLoS ONE. 7 (6), creators-Schalkwyk=3ALeonard_C=3A=3A

Malki, K., Lourdusamy, A., Binder, E., Pay谩-Cano, J., Sluyter, F., Craig, I., Keers, R., McGuffin, P., Uher, R. and Schalkwyk, LC., (2012). . Pharmacogenetics and Genomics. 22 (11), 765-776

Malki, K., Campbell, J., Davies, M., Keers, R., Uher, R., Ward, M., Paya鈥怌ano, J., Aitchinson, KJ., Binder, E., Sluyter, F., Kuhn, K., Selzer, S., Craig, I., McGuffin, P. and Schalkwyk, LC., (2012). . PROTEOMICS. 12 (14), 2355-2365

Powell, TR., Fernandes, C. and Schalkwyk, LC., (2012). Depression鈥怰elated Behavioral Tests. Current Protocols in Mouse Biology. 2 (2), 119-127

Dempster, EL., Pidsley, R., Schalkwyk, LC., Owens, S., Georgiades, A., Kane, F., Kalidindi, S., Picchioni, M., Kravariti, E., Toulopoulou, T., Murray, RM. and Mill, J., (2011). . Human Molecular Genetics. 20 (24), 4786-4796

K玫ks, S., Soomets, U., Plaas, M., Terasmaa, A., Noormets, K., Tillmann, V., Vasar, E., Fernandes, C. and Schalkwyk, LC., (2011). . Physiological Genomics. 43 (24), 1351-1358

Binder, E., Malki, K., Paya-Cano, JL., Fernandes, C., Aitchison, KJ., Math茅, AA., Sluyter, F. and Schalkwyk, LC., (2011). . Pharmacogenetics and Genomics. 21 (12), 779-789

Malki, K., Uher, R., Paya-Cano, J., Binder, E., Rietschel, M., Zobel, A., Mors, O., Hauser, J., Henigsberg, N., Jerman, B., Souery, D., Placentino, A., Ng, MY., Cohen-Woods, S., Sluyter, F., Farmer, A., Aitchison, KJ., Craig, IW., Lewis, CM., McGuffin, P. and Schalkwyk, LC., (2011). . Biological Psychiatry. 69 (4), 360-365

Sikk, K., (2011). . Frontiers in Genetics. 2 (AUG), 42-

Kember, RL., Fernandes, C., Tunbridge, EM., Liu, L., Pay谩鈥怌ano, JL., Parsons, MJ. and Schalkwyk, LC., (2010). . Genes, Brain and Behavior. 9 (8), 925-932

Docherty, SJ., Davis, OSP., Kovas, Y., Meaburn, EL., Dale, PS., Petrill, SA., Schalkwyk, LC. and Plomin, R., (2010). . Genes, Brain and Behavior. 9 (2), 234-247

K玫ks, S., Velthut, A., Sarapik, A., Altm盲e, S., Reinmaa, E., Schalkwyk, LC., Fernandes, C., Lad, HV., Soomets, U., Jaakma, 脺. and Salumets, A., (2010). . MHR: Basic science of reproductive medicine. 16 (4), 229-240

Meaburn, EL., Schalkwyk, LC. and Mill, J., (2010). . Epigenetics. 5 (7), 578-582

Davies, MN., Meaburn, EL. and Schalkwyk, LC., (2010). . Briefings in Functional Genomics. 9 (5-6), 385-390

Schalkwyk, LC., Meaburn, EL., Smith, R., Dempster, EL., Jeffries, AR., Davies, MN., Plomin, R. and Mill, J., (2010). . The American Journal of Human Genetics. 86 (2), 196-212

Davis, OSP., Butcher, LM., Docherty, SJ., Meaburn, EL., Curtis, CJC., Simpson, MA., Schalkwyk, LC. and Plomin, R., (2010). . Behavior Genetics. 40 (6), 759-767

Lad, HV., Liu, L., Paya-Cano, JL., Parsons, MJ., Kember, R., Fernandes, C. and Schalkwyk, LC., (2010). . Physiology & Behavior. 99 (3), 301-316

Schosser, A., Pirlo, K., Gaysina, D., Cohen-Woods, S., Schalkwyk, LC., Elkin, A., Korszun, A., Gunasinghe, C., Gray, J., Jones, L., Meaburn, E., Farmer, AE., Craig, IW. and McGuffin, P., (2010). Utility of the pooling approach as applied to whole genome association scans with high-density Affymetrix microarrays. BMC Research Notes. 3 (1), 274-

Ronald, A., Butcher, LM., Docherty, S., Davis, OSP., Schalkwyk, LC., Craig, IW. and Plomin, R., (2010). . Behavior Genetics. 40 (1), 31-45

Ronald, A., Butcher, LM., Docherty, SJ., Davis, OSP., Schalkwyk, LC., Craig, IW. and Plomin, R., (2010). . Behavior Genetics. 40 (1), 48-48

K玫ks, S., Soomets, U., Paya-Cano, JL., Fernandes, C., Luuk, H., Plaas, M., Terasmaa, A., Tillmann, V., Noormets, K., Vasar, E. and Schalkwyk, LC., (2009). . Physiological Genomics. 37 (3), 249-259

Meaburn, EL., Fernandes, C., Craig, IW., Plomin, R. and Schalkwyk, LC., (2009). . Twin Research and Human Genetics. 12 (4), 372-380

Davis, OSP., Plomin, R. and Schalkwyk, LC., (2009). . Bioinformatics. 25 (2), 281-283

Smith, RG., Kember, RL., Mill, J., Fernandes, C., Schalkwyk, LC., Buxbaum, JD. and Reichenberg, A., (2009). . PLoS ONE. 4 (12), e8456-e8456

Kas, MJH., Gelegen, C., Schalkwyk, LC. and Collier, DA., (2009). . American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 150B (3), 309-317

Overall, R., (2009). Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource. Frontiers in Neuroscience. 3 (NOV), 55-

Davies, MN., Lawn, S., Whatley, S., Fernandes, C., Williams, RW. and Schalkwyk, LC., (2009). . Frontiers in Neuroscience. 3 (OCT), 54-

Meaburn, EL., Harlaar, N., Craig, IW., Schalkwyk, LC. and Plomin, R., (2008). . Molecular Psychiatry. 13 (7), 729-740

K玫ks, S., Fernandes, C., Kurrikoff, K., Vasar, E. and Schalkwyk, LC., (2008). . Behavioural Brain Research. 188 (1), 62-70

Parsons, MJ., Grimm, CH., Paya-Cano, JL., Sugden, K., Nietfeld, W., Lehrach, H. and Schalkwyk, LC., (2008). . Mammalian Genome. 19 (7-8), 552-560

Schalkwyk, LC., Fernandes, C., Nash, MW., Kurrikoff, K., Vasar, E. and K玫ks, S., (2007). . Genes, Brain and Behavior. 6 (3), 299-303

Kas, MJH., Fernandes, C., Schalkwyk, LC. and Collier, DA., (2007). . Molecular Psychiatry. 12 (4), 324-330

Lad, HV., Liu, L., Pay谩-Cano, JL., Fernandes, C. and Schalkwyk, LC., (2007). . Mammalian Genome. 18 (6-7), 482-491

Plomin, R. and Schalkwyk, LC., (2007). . Developmental Science. 10 (1), 19-23

Caspi, A., Williams, B., Kim-Cohen, J., Craig, IW., Milne, BJ., Poulton, R., Schalkwyk, LC., Taylor, A., Werts, H. and Moffitt, TE., (2007). . Proceedings of the National Academy of Sciences. 104 (47), 18860-18865

Docherty, SJ., Butcher, LM., Schalkwyk, LC. and Plomin, R., (2007). . BMC Genomics. 8 (1), 214-214

Sugden, K., D'Souza, UM., Aitchison, KJ., Schalkwyk, LC., McGuffin, P., Byers, H., Campbell, J., Hye, A. and Pariante, CM., (2007). . European Neuropsychopharmacology. 17, S27-S28

Fernandes, C., Hoyle, E., Dempster, E., Schalkwyk, LC. and Collier, DA., (2006). . Genes, Brain and Behavior. 5 (6), 433-440

Meaburn, E., Butcher, LM., Schalkwyk, LC. and Plomin, R., (2006). . Nucleic Acids Research. 34 (4), creators-Schalkwyk=3ALeonard_C=3A=3A

D'Souza, U., Sugden, K., Aitchison, KJ., Schalkwyk, LC., McGuffin, P. and Pariante, M., (2006). . European Neuropsychopharmacology. 16, S187-S187

Galsworthy, MJ., Paya-Cano, JL., Liu, L., Monle贸n, S., Gregoryan, G., Fernandes, C., Schalkwyk, LC. and Plomin, R., (2005). . Behavior Genetics. 35 (5), 675-692

Butcher, LM., Meaburn, E., Knight, J., Sham, PC., Schalkwyk, LC., Craig, IW. and Plomin, R., (2005). . Human Molecular Genetics. 14 (10), 1315-1325

Butcher, LM., Meaburn, E., Dale, PS., Sham, P., Schalkwyk, LC., Craig, IW. and Plomin, R., (2005). . Molecular Psychiatry. 10 (4), 384-392

Simpson, CL., Knight, J., Butcher, LM., Hansen, VK., Meaburn, EL., Schalkwyk, LC., Craig, IW., Powell, JF., Sham, PC. and Al-Chalabi, A., (2005). . Nucleic Acids Research. 33 (3), e25-e25

Meaburn, E., Butcher, LM., Liu, L., Fernandes, C., Hansen, V., Al-Chalabi, A., Plomin, R., Craig, I. and Schalkwyk, LC., (2005). . BMC Genomics. 6 (1), creators-Schalkwyk=3ALeonard_C=3A=3A

Butcher, LM., Meaburn, E., Liu, L., Fernandes, C., Hill, L., Al-Chalabi, A., Plomin, R., Schalkwyk, L. and Craig, IW., (2004). . Behavior Genetics. 34 (5), 549-555

Stolerman, IP., Chamberlain, S., Bizarro, L., Fernandes, C. and Schalkwyk, L., (2004). . Neuropharmacology. 46 (3), 363-371

Nyberg, J., Sandnabba, K., Schalkwyk, L. and Sluyter, F., (2004). . Genes, Brain and Behavior. 3 (2), 101-109

Fernandes, C., Liu, L., Paya-Cano, JL., Gregorov锟, SA., Forejt, J. and Schalkwyk, LC., (2004). . Behavior Genetics. 34 (6), 621-630

Fernandes, C., Paya鈥怌ano, JL., Sluyter, F., D'Souza, U., Plomin, R. and Schalkwyk, LC., (2004). . European Journal of Neuroscience. 19 (9), 2576-2582

(2004). . Nature Genetics. 36 (11), 1133-1137

Ben Abdelkhalek, H., Beckers, A., Schuster-Gossler, K., Pavlova, MN., Burkhardt, H., Lickert, H., Rossant, J., Reinhardt, R., Schalkwyk, LC., M眉ller, I., Herrmann, BG., Ceolin, M., Rivera-Pomar, R. and Gossler, A., (2004). . Genes & Development. 18 (14), 1725-1736

Craig, IW., Mill, J., Craig, GM., Loat, C. and Schalkwyk, LC., (2004). . European Journal of Human Genetics. 12 (8), 639-646

Sluyter, F. and Schalkwyk, LC., (2003). . Behavior Genetics. 33 (5), 457-460

(2003). . Nature Reviews Genetics. 4 (11), 911-916

Mill, J., Galsworthy, MJ., Paya鈥怌ano, JL., Sluyter, F., Schalkwyk, LC., Plomin, R. and Asherson, P., (2002). . Genes, Brain and Behavior. 1 (3), 166-173

Klose, J., Nock, C., Herrmann, M., St眉hler, K., Marcus, K., Bl眉ggel, M., Krause, E., Schalkwyk, LC., Rastan, S., Brown, SDM., B眉ssow, K., Himmelbauer, H. and Lehrach, H., (2002). . Nature Genetics. 30 (4), 385-393

Schalkwyk, LC., Cusack, B., Dunkel, I., Hopp, M., Kramer, M., Palczewski, S., Piefke, J., Scheel, S., Weiher, M., Wenske, G., Lehrach, H. and Himmelbauer, H., (2001). . Genome Research. 11 (12), 2142-2150

Ryu, S., Cho, S., Park, S., Lim, W., Kim, M., Hong, S., Bae, D., Park, Y., Kim, B., Kim, H. and Yun, H., (2001). Cloning of the cel 9A gene and characterization of its gene product from marine bacterium Pseudomonas sp. SK38. Applied Microbiology and Biotechnology. 57 (1-2), 138-145

Leong, WL., Dobson, MJ., Logsdon, Jr., JM., Abdel-Majid, RM., Schalkwyk, LC., Guernsey, DL. and Neumann, PE., (2000). . Mammalian Genome. 11 (2), 97-103

G枚sele, C., Hong, L., Kreitler, T., Rossmann, M., Hieke, B., Gro脽, U., Kramer, M., Himmelbauer, H., Bihoreau, M-T., Kwitek-Black, AE., Twigger, S., Tonellato, PJ., Jacob, HJ., Schalkwyk, LC., Lindpaintner, K., Ganten, D., Lehrach, H. and Knoblauch, M., (2000). . Genomics. 69 (3), 287-294

Knoblauch, M., G枚sele, C., Zimdahl, H., Hieke, B., Himmelbauer, H., Schalkwyk, L., Lindpaintner, K., Ganten, D. and Lehrach, H., (2000). . Journal of Experimental Animal Science. 41 (1-2), 35-37

Himmelbauer, H., (2000). Interspersed repetitive sequence (IRS)-PCR for typing of whole genome radiation hybrid panels. Nucleic Acids Research. 28 (2), 7e-7

Zhu, B., Smith, JA., Tracey, SM., Konfortov, BA., Welzel, K., Schalkwyk, LC., Lehrach, H., Kollers, S., Masabanda, J., Buitkamp, J., Fries, R., Williams, JL. and Miller, JR., (1999). . Mammalian Genome. 10 (7), 706-709

Hills, D., Tracey, S., Masabanda, J., Fries, R., Schalkwyk, LC., Lehrach, H., Miller, JR. and Williams, JL., (1999). . Mammalian Genome. 10 (8), 837-838

Nock, C., Gauss, C., Schalkwyk, LC., Klose, J., Lehrach, H. and Himmelbauer, H., (1999). Technology development at the interface of proteome research and genomics: Mapping nonpolymorphic proteins on the physical map of mouse chromosomes. Electrophoresis. 20 (4-5), 1027-1032

Nock, C., Gauss, C., Schalkwyk, LC., Klose, J., Lehrach, H. and Himmelbauer, H., (1999). . Electrophoresis. 20 (4-5), 1027-1032

Schalkwyk, LC., Jung, M., Daser, A., Weiher, M., Walter, J., Himmelbauer, H. and Lehrach, H., (1999). . Genome Research. 9 (9), 878-887

Schalkwyk, LC., Himmelbauer, H. and Lehrach, H., (1999). . Archiv fur Tierzucht. 42 (6 SUPPL.), 67-73

Buitkamp, J., Ewald, D., Schalkwyk, L., Weiher, M., Masabanda, J., Sazanov, A., Lehrach, H. and Fries, R., (1998). . Animal Genetics. 29 (4), 295-301

Priestley, A., (1998). . Nucleic Acids Research. 26 (8), 1965-1973

Schalkwyk, LC., Weiher, M., Kirby, M., Cusack, B., Himmelbauer, H. and Lehrach, H., (1998). . Mammalian Genome. 9 (10), 807-811

Himmelbauer, H., Wedemeyer, N., Haaf, T., Wanker, EE., Schalkwyk, LC. and Lehrach, H., (1998). . Mammalian Genome. 9 (1), 26-31

Himmelbauer, H., Dunkel, I., Otto, GW., Burgtorf, C., Schalkwyk, LC. and Lehrach, H., (1998). . Mammalian Genome. 9 (8), 611-616

Abdel-Majid, RM., Leong, WL., Schalkwyk, LC., Smallman, DS., Wong, ST., Storm, DR., Fine, A., Dobson, MJ., Guernsey, DL. and Neumann, PE., (1998). . Nature Genetics. 19 (3), 289-291

Toye, AA., Schalkwyk, L., Lehrach, H. and Bumstead, N., (1997). . Mammalian Genome. 8 (4), 274-276

Crnogorac-Jurcevic, T., Brown, JR., Lehrach, H. and Schalkwyk, LC., (1997). . Genomics. 41 (2), 177-184

Cai, L., Schalkwyk, LC., Schoeberlein-Stehli, A., Zee, RYL., Smith, A., Haaf, T., Georges, M., Lehrach, H. and Lindpaintner, K., (1997). . Genomics. 39 (3), 385-392

Hunter, KW., Riba, L., Schalkwyk, L., Clark, M., Resenchuk, S., Beeghly, A., Su, J., Tinkov, F., Lee, P., Ramu, E., Lehrach, H. and Housman, D., (1996). . Genome Research. 6 (4), 290-299

McCarthy, L., Hunter, K., Schalkwyk, L., Riba, L., Anson, S., Mott, R., Newell, W., Bruley, C., Bar, I. and Ramu, E., (1995). . Proceedings of the National Academy of Sciences. 92 (12), 5302-5306

Schalkwyk, LC., Francis, F. and Lehrach, H., (1995). Techniques in mammalian genome mapping. Current Opinion in Biotechnology. 6 (1), 37-43

Breen, M., Deakin, L., Macdonald, B., Miller, S., Sibson, R., Tarttelin, E., Avner, P., Bourgade, F., Guenet, JL., Montagutelli, X., Poirier, C., Simon, D., Tailor, D., Bishop, M., Kelly, M., Rysavy, F., Rastan, S., Norris, D., Shepherd, D., Abbott, C., Pilz, A., Hodge, S., Jackson, I., Boyd, Y., Blair, H., Maslen, G., Todd, JA., Reed, PW., Stoye, J., Ashworth, A., McCarthy, L., Cox, R., Schalkwyk, LC., Lehrach, H., Klose, J., Gangadharan, U. and Brown, S., (1994). . Human Molecular Genetics. 3 (4), 621-627

A.Jones, K., M.Black, D., A.Brown, M., L.Griffiths, B., M.Nicolai, H., A.Chambers, J., Bonjardim, M., Xu, C-F., Boyd, M., MeFariane, R., Korn, B., Poustka, A., A.North, M., Schalkwyk, L., Lehrach, H. and Solomon, E., (1994). . Human Molecular Genetics. 3 (11), 1927-1934

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Schalkwyk, LC., Charlebois, RL. and Doolittle, WF., (1993). . Canadian Journal of Microbiology. 39 (2), 201-206

Schalkwyk, LC., (1993). Chapter 15 Halobacterial genes and genomes. New Comprehensive Biochemistry. 26 (C), 467-496

Cohen, A., Lam, WL., Charlebois, RL., Doolittle, WF. and Schalkwyk, LC., (1992). . Proceedings of the National Academy of Sciences. 89 (5), 1602-1606

Doolittle, WF., Lam, WL., Schalkwyk, LC., Charlebois, RL., Cline, SW. and Cohen, A., (1992). . Biochemical Society symposium. 58 (58), 73-78

Charlebois, RL., Schalkwyk, LC., Hofman, JD. and Doolittle, WF., (1991). . Journal of Molecular Biology. 222 (3), 509-524

Charlebois, RL., Hofman, JD., Schalkwyk, LC., Lam, WL. and Doolittle, WF., (1989). . Canadian Journal of Microbiology. 35 (1), 21-29

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Book chapters (1)

Nock, C., Gauss, C., Schalkwyk, LC., Klose, J., Lehrach, H. and Himmelbauer, H., (1999). Technology development at the interface of proteome research and genomics: Mapping nonpolymorphic proteins on the physical map of mouse chromosomes. In: From Genome to Proteome: Advances in the Practice & Application of Proteomics. Wiley. 447- 452. 9783527301546

Conferences (42)

Mill, J., Hannon, E., Dempster, E., Franklin, A., Burrage, J., Davies, J., Chioza, B., Commin, G., Jeffries, AR., Bamford, RA. and Schalkwyk, L., (2023). W76. CELL-SPECIFIC METHYLOMIC VARIATION IN NEURODEVELOPMENT AND SCHIZOPHRENIA

Hannon, E., Davies, J., Chioza, B., Policicchio, S., Burrage, J., Commin, G., Jeffries, AR., Schalkwyk, L., Dempster, E. and Mill, J., (2022). 89. IDENTIFYING CELL-TYPE-SPECIFIC EPIGENETIC VARIATION IN THE CORTEX ASSOCIATED WITH SCHIZOPHRENIA

Shireby, G., Hannon, E., Commin, G., Burrage, J., Davies, J., Policicchio, S., Schalkwyk, L., Dempster, E. and Mill, J., (2021). TH44. LEVERAGING DNA METHYLATION QUANTITATIVE-TRAIT LOCI TO CHARACTERIZE THE RELATIONSHIP BETWEEN METHYLOMIC VARIATION, GENE EXPRESSION, AND PSYCHIATRIC DISEASE

Asenius, F., Marzi, SJ., Gorrie-Stone, TJ., Brew, A., Panchbaya, Y., Williamson, E., Schalkwyk, L., Rakyan, V. and Williams, DJ., (2020). A lack of DNA methylation covariation between human blood and sperm make it unlikely to mediate intergenerational inheritance of acquired traits

Hannon, E., Dempster, E., Burrage, J., Curtis, C., Gillespie, A., Dempster, D., Gunasinghe, C., Schalkwyk, L., Gaughran, F., Murray, R., Di Forti, M., Collier, D., Breen, G. and Mill, J., (2017). AN EPIGENOME-WIDE ASSOCIATION STUDY OF CLOZAPINE USE IN TREATMENT-RESISTANT SCHIZOPHRENIA

Rutten, B., Vermetten, E., Vinkers, C., Pishva, E., Kenis, G., de Nijs, L., Eijssen, L., Viechtbauer, W., van den Hove, D., Schraut, K., Lesch, K-P., Daskalakis, N., Yehuda, R., Schalkwyk, L., Lunnon, K., Mill, J., Nievergelt, C., Baker, DS., Geuze, E. and Boks, MPM., (2015). Blood-based DNA Methylation Signatures of Susceptibility to Traumatic Stress; Results From A Dutch Prospective Military Cohort Study

Spiers, H., Bray, NJ., Hannon, E., Schalkwyk, LC., Wong, CC., Pidsley, R., Smith, RG. and Mill, J., (2015).

Boks, MPM., van Mierlo, H., Rutten, BPF., Radstake, TRDJ., De Witte, LD., Geuze, E., Horvath, S., Schalkwyk, LC., Vinkers, CH., Broen, JCA. and Vermetten, E., (2015). Longitudinal Changes of Telomere Length and Epigenetic Age Related to Traumatic Stress and Post-traumatic Stress Disorder

Powell, TR., Schalkwyk, LC., Breen, G., Lawrence, T., Pariante, C., McGuffin, P., Tansey, K., Uher, R. and D'Souza, UM., (2012). Identifying transcriptomic biomarkers for response to escitalopram in the inflammatory cytokine pathway

K玫ks, S., Velthut, A., Sarapik, A., Altm盲e, S., Reinmaa, E., Schalkwyk, LC., Fernandes, C., Lad, H., Soomets, U., Jaakma, 脺W. and Salumets, A., (2011). 166 THE DIFFERENTIAL TRANSCRIPTOME AND ONTOLOGY PROFILES OF MURAL AND CUMULUS GRANULOSA CELLS IN STIMULATED HUMAN ANTRAL FOLLICLES

Sikk, K., Koks, S., Soomets, U., Schalkwyk, LC., Fernandes, C., Haldre, S., Aquilonius, S-M. and Taba, P., (2010). Peripheral blood RNA gene expression profiling in illicit methcathinone users reveals effect on immune system

Amos-Landgraf, J. and Schalkwyk, LC., (2008). The 21st International Mammalian Genome Conference Meeting Report

Meaburn, E., Harlaar, N., Craig, IW., Schalkwyk, LC. and Plomin, R., (2007).

Binder, E., Paya-Cano, JL., Sluyter, F. and Schalkwyk, LC., (2006).

Paya-Cano, JL., Sluyter, F., Mineur, YS., Fernandes, C., Crusio, WE. and Schalkwyk, LC., (2006).

Meaburn, E., Butcher, LM., Harlaar, N., Curtis, C., Craig, IW., Schalkwyk, LC. and Plomin, R., (2006).

Huezo-Diaz, P., Williamson, R., Nash, MW., Sim, SC., Alhberg, S., Hoda, F., Rietschel, M., Schmal, C., Farmer, A., Schulze, T., Hauser, J., Henigsberg, N., Maier, W., Zobel, A., Larsen, ER., Mors, O., Mendelewicz, J., Marusic, A., Perez, J., Schalkwyk, L., McGuffin, P., Craig, I., Ingelman-Sundberg, M. and Aitchison, KJ., (2006).

D'Souza, UM., Sugden, K., Pariante, CM., Byers, H., Ward, M., Schalkwyk, LC., McGuffin, P. and Aitchison, KJ., (2006).

Butcher, LM., Meaburn, EL., Craig, IW., Schalkwyk, LC. and Plomin, R., (2006).

D'Souza, UM., Sugden, K., Pariante, CM., Byers, H., Ward, M., Schalkwyk, LC., McGuffin, P. and Aitchison, KJ., (2006). Effects of antidepressant treatment on gene expression in mouse cultured cells

Liu, L., Fernandes, C., Brookes, K., Paya-Capo, J., Asherson, P. and Schalkwyk, LC., (2005).

Meaburn, EL., Butcher, LM., Knight, J., Craig, I., Schalkwyk, LC. and Plomin, R., (2005).

Butcher, LM., Meaburn, E., Knight, J., Sham, PC., Schalkwyk, LC., Craig, IW. and Plomin, R., (2005).

Butcher, LM., Meaburn, E., Knight, J., Sham, PC., Schalkwyk, LC., Craig, IW. and Plomin, R., (2005).

Sugden, K., D'Souza, UM., McGuffin, P., Schalkwyk, LC., Aitchison, KJ. and Pariante, CM., (2005).

Fernandes, C., Liu, L., Paya-Cano, JL., Whatley, SA. and Schalkwyk, LC., (2004).

Meaburn, EL., Butcher, ML., Liu, L., Fernandes, C., Sham, P., Plomin, R., Craig, I. and Schalkwyk, L., (2004).

Chamberlain, S., Bizarro, L., Fernandes, C., Schalkwyk, L. and Stolerman, IP., (2003). Nicotinic receptors containing the alpha7 subunit do not contribute to nicotine discrimination

Sluyter, F. and Schalkwyk, LC., (2003). Symposium: Using microarrays in the analysis of behavior

Fernandes, C., Paya-Cano, J., Sluyter, F., D'Souza, U., Plomin, R. and Schalkwyk, LC., (2003). The power of gene expression profiling and mouse models to unravel behavior.

Meaburn, E., Schalkwyk, L., Criag, I. and Plomin, R., (2003). A genome wide scan using 400 non-synonymous SNP markers in DNA pools identifies genes associated with language impairment in children

Meaburn, EK., Butcher, LM., Schalkwyk, L., Craig, I. and Plomin, R., (2002). Localisation of quantitative trait loci responsible for the heritability of language impairment using DNA pooling

Hill, L., Meaburn, E., Butcher, LM., Schalkwyk, L., Craig, IW. and Plomin, R., (2002). A genome scan using non-synonymous SNPs in coding regions and general cognitive ability

Galsworthy, MJ., Paya-Cano, JL., Liu, L., Fernandes, C., Schalkwyk, L. and Plomin, R., (2002). The reliabilities, interrelationships and quantitative genetics of cognitive tasks in mus musculus: A study of 250 heterogeneous stock mice

Tandon, K., Schalkwyk, L., Patel, M., Kinirons, M., Kerwin, R., McGuffin, P. and Aitchison, KJ., (2002).

Tandon, K., Schalkwyk, LC., Checkley, S., Patel, M., Kinirons, M., Kerwin, RW., McGuffin, P. and Aitchison, KJ., (2002).

Butcher, LM., Meaburn, EL., Hill, L., Plomin, R. and Schalkwyk, L., (2002). How many non-synonymous SNPS are available on public databases?

Tandon, K., Schalkwyk, L., Checkley, S., Patel, M., Kinirons, M., Kerwin, RW., McGuffin, P. and Aitchison, KJ., (2002). CYP2D6 genotype and treatment with tricyclic antidepressants

Meaburn, EL., Plomin, R. and Schalkwyk, L., (2001). Single nucleotide polymorphism genotyping in DNA pools.

Vettakkorumakankav, NN., Stevenson, KJ., Schalkwyk, LC. and Doolittle, WF., (1994). Disruption of the gene coding for dihydrolipoamide dehydrogenase in Haloferax volcanii by homologous recombination.

ROSS, MT., KNIGHTS, CJ., ROEST CROLLIUS, H., LABELLA, T., HOLLOWAY, E., MIFSUD, J., LI, K., LAM, V., VATCHEVA, R., KUMLEIN, J., FRANCIS, F., MOTT, R., SCHALKWYK, L., BHOGAL, R., ZEHETNER, G. and LEHRACH, H., (1993). BUILDING AN INTEGRATED PHYSICAL AND GENETIC-MAP OF THE HUMAN X-CHROMOSOME

DOOLITTLE, WF., CHARLEBOIS, RL., SCHALKWYK, LC., LAM, WL., CONOVER, RK., TSOULUHAS, D., CLINE, SW., HOFMAN, JD. and COHEN, A., (1991).

Reports and Papers (3)

Wang, Y., Gorrie-Stone, TJ., Grant, OA., Andrayas, AD., Zhai, X., McDonald-Maier, KD. and Schalkwyk, LC., (2021). interpolatedXY: a two-step strategy to normalise DNA methylation microarray data avoiding sex bias

Wang, Y., Hannon, E., Grant, OA., Gorrie-Stone, TJ., Kumari, M., Mill, J., Zhai, X., McDonald-Maier, KD. and Schalkwyk, LC., (2020). DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy

Hannon, E., Gorrie-Stone, T., Smart, M., Burrage, J., Hughes, A., Bao, Y., Kumari, M., Schalkwyk, L. and Mill, J., (2018). Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits

Other (15)

Hannon, E., Bray, N., Weedon, M., Gorrie-Stone, T., Smart, M., Kumari, M., Schalkwyk, L., O'Donovan, M. and Mill, J., (2019).PLEIOTROPIC EFFECTS OF GENETIC VARIATION ASSOCIATED WITH PSYCHIATRIC DISORDERS ON DNA METHYLATION. European Neuropsychopharmacology. 29,Elsevier BV

Hannon, E., Dempster, E., Burrage, J., McQuillin, A., Clair, DS., Morris, D., Di Forti, M., Gaughran, F., MacCabe, J., Breen, G., Collier, D., Murray, R., Schalkwyk, L. and Mill, J., (2019).AN INTEGRATED GENETIC-EPIGENETIC ANALYSIS OF SCHIZOPHRENIA: EVIDENCE FOR CO-LOCALIZATION OF GENETIC ASSOCIATIONS AND DIFFERENTIAL DNA METHYLATION FROM A LARGE META-ANALYSIS OF WHOLE BLOOD DNA. European Neuropsychopharmacology. 29,Elsevier BV

Mill, J., Hannon, E., Spiers, H., Wong, CCY., Viana, J., O'Donovan, M., Schalkwyk, L. and Bray, N., (2019).Regulatory Genomic Variation In The Developing Brain: Relevance To Neuropsychiatric Phenotypes. European Neuropsychopharmacology. 29,Elsevier BV

Hannon, E., Marzi, S., Schalkwyk, L. and Mill, J., (2019).F61GENETIC RISK VARIANTS FOR BRAIN DISORDERS ARE SIGNIFICANTLY ENRICHED IN ACTIVE ENHANCERS IN THE CORTEX. European Neuropsychopharmacology. 29,Elsevier BV

Hannon, E., Dempster, E., Mansell, G., Schalkwyk, L., Murray, R., McQuillin, A., Kowalec, K., Clair, DS., Morris, D., Sullivan, P., O'Donovan, M., MacCabe, J., Collier, D. and Mill, J., (2019).57METHYLOMIC BIOMARKERS OF SCHIZOPHRENIA AND ANTIPSYCHOTIC MEDICATION EXPOSURE. European Neuropsychopharmacology. 29,Elsevier BV

O'Brien, H., Hannon, E., Hill, M., Toste, C., Robertson, M., Morgan, J., McLaughlin, G., Lewis, C., Schalkwyk, L., Pardinas, A., Owen, M., O'Donovan, M., Mill, J. and Bray, N., (2019).55EXPRESSION QUANTITATIVE TRAIT LOCI IN THE DEVELOPING HUMAN BRAIN AND THEIR ENRICHMENT IN NEUROPSYCHIATRIC DISORDERS. European Neuropsychopharmacology. 29,Elsevier BV

Richmond, RC., Bao, Y., Smart, M., Gorrie-Stone, T., Schalkwyk, L., Mill, J., Davey Smith, G., Benzeval, M., Relton, C. and Kumari, M., (2018).P8鈥匢nvestigating epigenetic differences in response to shift work: findings fromunderstanding society(UK longitudinal household survey). Poster presentations. 72,BMJ Publishing Group Ltd

Hannon, E., Lunnon, K., Schalkwyk, L. and Mill, J., (2017).CHARACTERIZING INTER-INDIVIDUAL VARIATION IN DNA METHYLATION BETWEEN BLOOD AND BRAIN: IMPLICATIONS FOR EPIGENETIC STUDIES OF PSYCHIATRIC PHENOTYPES. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27

Hannon, E., Spiers, H., Viana, J., Pidsley, R., Burrage, J., Murphy, T., Troakes, C., Turecki, G., O'Donovan, M., Schalkwyk, L., Bray, NJ. and Mill, J., (2017).METHYLATION QUANTITATIVE TRAIT LOCI (MQTL) IN THE DEVELOPING HUMAN BRAIN AND THEIR ENRICHMENT IN GENOMIC REGIONS ASSOCIATED WITH SCHIZOPHRENIA. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27

Viana, J., Pidsley, R., Hannon, E., Spiers, H., Troakes, C., Al-Saraj, S., Mechawar, N., Turecki, G., Schalkwyk, L., Bray, NJ. and Mill, J., (2017).INVESTIGATING EPIGENOMIC REGULATION IN SCHIZOPHRENIA. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27

Xia, B., Kepa, A., Colvert, E., Mea-burn, E., Ronald, A., Schalkwyk, L., Mill, J., Plomin, R., Happe, F. and Wong, CCY., (2017).AN INVESTIGATION OF X-CHROMOSOME INACTIVATION PROFILES USING A GENETICALLY SENSITIVE DISCORDANT TWIN DESIGN. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27

Hannon, E., Dempster, E., Burrage, J., Smith, A., Gurling, H., Basso, N., McQuillin, A., Schalkwyk, L. and Mill, J., (2017).AN INTEGRATED GENETIC-EPIGENETIC ANALYSIS OF SCHIZOPHRENIA. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27

Dempster, E., Hannon, E., Schalkwyk, L., Bohlken, M., Kaprio, J., Toulopoulou, T., Spector, T., Hulshoffpol, H., Nenadic, I., Cannon, T., Hultman, C., Murray, R. and Mill, J., (2017).GENOME-WIDE METHYLOMIC ANALYSIS OF MONOZYGOTIC TWINS DISCORDANT FOR SCHIZOPHRENIA. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27

Wong, CCY., Parikshak, N., Spiers, H., Brays, NJ., Lysenko, L., Troakes, C., Viana, J., Hannon, E., Schalkwyk, L., Geschwind, D. and Mill, J., (2017).METHYLOMIC ANALYSIS OF AUTISM BRAIN: DISEASE ASSOCIATED VARIATION AND SUPPORT FOR A NEURODEVELOPMENTAL COMPONENT TO ETIOLOGY. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27

Spiers, H., Hannon, E., Schalkwyk, L., Bray, N. and Mill, J., (2017).DNA HYDROXYMETHYLATION ASSOCIATED WITH HUMAN FETAL BRAIN DEVELOPMENT. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27

Grants and funding

2022

Mapping cell-type-specific regulatory genomic variation in Alzheimer's disease pathology.

Medical Research Council

2020

Building an Autism Research Network in Vietnam

糖心Vlog (GCRF)

2017

Regulatory genomic profiling in schizophrenia

Medical Research Council

2014

Methylomic Profiling in Schizophrenia: Towards an Integrated Genetic-Epigenetic Approach

Medical Research Council

Contact

lschal@essex.ac.uk

Location:

3SW.4.34, Colchester Campus

More about me
Genomics and Computational Biology Group: