Professor Leonard Schalkwyk

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Email
lschal@essex.ac.uk -
Location
3SW.4.34, Colchester Campus
Profile
Biography
Originally a microbiologist from Canada, Leo studied at the University of Alberta, graduating in 1983. His PhD (Dalhousie University, 1991) was on genome mapping of Haloferax, an archaeon from the Dead Sea. He worked on genomic resources for several species and genome mapping of mouse in Hans Lehrach's laboratory at the Imperial Cancer Research Fund laboratory in London and at the Max-Planck-Institut für molekulare Genetik in Berlin. He was at the Social, Genetic and Developmental Psychiatry Research Centre, Kings College London from 2000-2014, where he worked on functional genomics and epigenomics, identifying genes involved in behaviour in the mouse and in depression, schizophrenia and Alzheimers disease in human. His research programme now includes epigenomics methods and environmental epigenomics as well as psychiatric epigenetics.
Qualifications
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1991 PhD in Biochemistry, Dalhousie University. Studies on the structure of the genome of Haloferax volcanii
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1983 BSc in Microbiology, University of Alberta
Appointments
糖心Vlog
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Professor of Human Genetics, School of Biological Sciences, 糖心Vlog (1/10/2014 - present)
Other academic
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Visiting Professor, SGDP, Institute of Psychiatry, Psychology and Neuroscience, King's College London (1/10/2014 - 30/9/2020)
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Reader in Functional Genomics, SGDP, Institute of Psychiatry, King's College London (1/1/2004 - 30/9/2014)
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Senior Lecturer in Molecular Genetics, SGDP, Institute of Psychiatry, King's College London (1/4/2000 - 31/12/2018)
Research and professional activities
Research interests
Genomic and epigenomic methods and software
Epigenomics and the environment
Alzheimers disease
Schizophrenia
Current research
DNA methylation profiles in human blood and brain, methods and software for epigenomic studies.
Conferences and presentations
Epigenetics Meets Social Neuroscience of Human Attachment
Keynote presentation, Organised one-day hybrid conference with about 100 participants, Colchester, United Kingdom, 5/7/2022
Functional Genomics and Epigenomics in Alzheimer鈥檚 disease
Invited presentation, Keynote presentation, ARUK East Network Scientific Meeting 2019, Cambridge, United Kingdom, 22/11/2019
Teaching and supervision
Previous supervision

Degree subject: Computer Science
Degree type: Doctor of Philosophy
Awarded date: 30/6/2023

Degree subject: Biological Sciences
Degree type: Doctor of Philosophy
Awarded date: 15/5/2023

Degree subject: Biosocial Research
Degree type: Doctor of Philosophy
Awarded date: 22/11/2022

Degree subject: Biochemistry
Degree type: Doctor of Philosophy
Awarded date: 8/10/2019

Degree subject: Biological Sciences
Degree type: Master of Science (by Dissertation)
Awarded date: 5/2/2018
Publications
Publications (2)
Grant, OA., Kumari, M., Schalkwyk, L. and Zabet, NR., (2024). Systematic investigation of interindividual variation of DNA methylation in human whole blood
Wang, Y., Grant, OA., Zhai, X., McDonald-Maier, KD. and Schalkwyk, LC., (2022). Recalibrating the cerebellum DNA methylation clock: implications for ageing rates comparison
Journal articles (181)
Dearman, A., Bao, Y., Schalkwyk, L. and Kumari, M., (2025). Serum proteomic correlates of mental health symptoms in a representative UK population sample. Brain, Behavior, & Immunity - Health. 44, 100947-100947
Hannon, E., Dempster, EL., Davies, JP., Chioza, B., Blake, GET., Burrage, J., Policicchio, S., Franklin, A., Walker, EM., Bamford, RA., Schalkwyk, LC. and Mill, J., (2024). Quantifying the proportion of different cell types in the human cortex using DNA methylation profiles. BMC Biology. 22 (1), 17-
Devall, M., Soanes, DM., Smith, AR., Dempster, EL., Smith, RG., Burrage, J., Iatrou, A., Hannon, E., Troakes, C., Moore, K., O'Neill, P., Al-Sarraj, S., Schalkwyk, L., Mill, J., Weedon, M. and Lunnon, K., (2023). . Frontiers in Endocrinology. 13, 1059120-
Wang, Y., Grant, O., Zhai, X., McDonald-Maier, K. and Schalkwyk, L., (2023). . GeroScience. 46 (1), 39-56
Vellame, DS., Shireby, G., MacCalman, A., Dempster, EL., Burrage, J., Gorrie-Stone, T., Schalkwyk, LS., Mill, J. and Hannon, E., (2023). . Epigenetics. 18 (1), 1217-1254
Flynn, R., Washer, S., Jeffries, AR., Andrayas, A., Shireby, G., Kumari, M., Schalkwyk, LC., Mill, J. and Hannon, E., (2022). . Human Molecular Genetics. 31 (18), 3181-3190
Wang, Y., Gorrie-Stone, TJ., Grant, OA., Andrayas, AD., Zhai, X., McDonald-Maier, KD. and Schalkwyk, LC., (2022). . Bioinformatics. 38 (16), 3950-3957
Grant, OA., Wang, Y., Kumari, M., Zabet, NR. and Schalkwyk, L., (2022). . Clinical Epigenetics. 14 (1), 62-
Bao, Y., Gorrie-Stone, T., Hannon, E., Hughes, A., Andrayas, A., Neilson, G., Burrage, J., Mill, J., Schalkwyk, L. and Kumari, M., (2022). . Scientific Reports. 12 (1), 22284-22284
Smith, RG., Pishva, E., Shireby, G., Smith, AR., Roubroeks, JAY., Hannon, E., Wheildon, G., Mastroeni, D., Gasparoni, G., Riemenschneider, M., Giese, A., Sharp, AJ., Schalkwyk, L., Haroutunian, V., Viechtbauer, W., van den Hove, DLA., Weedon, M., Brokaw, D., Francis, PT., Thomas, AJ., Love, S., Morgan, K., Walter, J., Coleman, PD., Bennett, DA., De Jager, PL., Mill, J. and Lunnon, K., (2021). . Nature Communications. 12 (1), 3517-
Min, JL., Hemani, G., Kumari, M., Schalkwyk, LC. and et al, (2021). . Nature Genetics. 53 (9), 1311-1321
Hannon, E., Dempster, EL., Mansell, G., Burrage, J., Bass, N., Bohlken, MM., Corvin, A., Curtis, CJ., Dempster, D., Di Forti, M., Dinan, TG., Donohoe, G., Gaughran, F., Gill, M., Gillespie, A., Gunasinghe, C., Hulshoff, HE., Hultman, CM., Johansson, V., Kahn, RS., Kaprio, J., Kenis, G., Kowalec, K., MacCabe, J., McDonald, C., McQuillin, A., Morris, DW., Murphy, KC., Mustard, CJ., Nenadic, I., O'Donovan, MC., Quattrone, D., Richards, AL., Rutten, BP., St Clair, D., Therman, S., Toulopoulou, T., Van Os, J., Waddington, JL., Wellcome Trust Case Control Consortium (WTCCC), CRESTAR consortium, Sullivan, P., Vassos, E., Breen, G., Collier, DA., Murray, RM., Schalkwyk, LS. and Mill, J., (2021). . eLife. 10, 1-53
Wang, Y., Hannon, E., Grant, O., Gorrie-Stone, T., Kumari, M., Mill, J., Zhai, X., McDonald-Maier, K. and Schalkwyk, L., (2021). . BMC Genomics. 22 (1), 484-
Leung, SK., Jeffries, AR., Castanho, I., Jordan, BT., Moore, K., Davies, JP., Dempster, EL., Bray, NJ., O'Neill, P., Tseng, E., Ahmed, Z., Collier, DA., Jeffery, ED., Prabhakar, S., Schalkwyk, L., Jops, C., Gandal, MJ., Sheynkman, GM., Hannon, E. and Mill, J., (2021). . Cell Reports. 37 (7), 110022-110022
脜senius, F., Gorrie-Stone, TJ., Brew, A., Panchbhaya, Y., Williamson, E., Schalkwyk, LC., Rakyan, VK., Holland, ML., Marzi, SJ. and Williams, DJ., (2020). . PLoS Genetics. 16 (10), e1009035-e1009035
Shireby, GL., Davies, JP., Francis, PT., Burrage, J., Walker, EM., Neilson, GWA., Dahir, A., Thomas, AJ., Love, S., Smith, RG., Lunnon, K., Kumari, M., Schalkwyk, LC., Morgan, K., Brookes, K., Hannon, E. and Mill, J., (2020). . Brain: a journal of neurology. 143 (12), 3763-3775
脜senius, F., Gorrie-Stone, TJ., Brew, A., Panchbaya, Y., Williamson, E., Schalkwyk, LC., Rakyan, VK., Holland, ML., Marzi, SJ. and Williams, DJ., (2020). DNA methylation covariation in human whole blood and sperm: implications for studies of intergenerational epigenetic effects
Gorrie-Stone, TJ., Smart, MC., Saffari, A., Malki, K., Hannon, E., Burrage, J., Mill, J., Kumari, M. and Schalkwyk, LC., (2019). . Bioinformatics. 35 (6), 981-986
Hannon, E., Marzi, SJ., Schalkwyk, LS. and Mill, J., (2019). . Molecular Brain. 12 (1), 7-
Hughes, A., Bao, Y., Smart, M., Gorrie-Stone, T., Hannon, E., Mill, J., Burrage, J., Schalkwyk, L. and Kumari, M., (2019). THE AUTHORS REPLY. American Journal of Epidemiology. 188 (2), 488-489
Mansell, G., Gorrie-Stone, TJ., Bao, Y., Kumari, M., Schalkwyk, LS., Mill, J. and Hannon, E., (2019). . BMC Genomics. 20 (1), 366-
Wong, CCY., Smith, RG., Hannon, E., Ramaswami, G., Parikshak, NN., Assary, E., Troakes, C., Poschmann, J., Schalkwyk, LC., Sun, W., Prabhakar, S., Geschwind, DH. and Mill, J., (2019). . Human Molecular Genetics. 28 (13), 2201-2211
Bell, CG., Lowe, R., Adams, PD., Baccarelli, AA., Beck, S., Bell, JT., Christensen, BC., Gladyshev, VN., Heijmans, BT., Horvath, S., Ideker, T., Issa, J-PJ., Kelsey, KT., Marioni, RE., Reik, W., Relton, CL., Schalkwyk, LC., Teschendorff, AE., Wagner, W., Zhang, K. and Rakyan, VK., (2019). . Genome Biology. 20 (1), 249-
El Khoury, LY., Gorrie-Stone, TJ., Smart, M., Hughes, A., Bao, Y., Andrayas, A., Burrage, J., Hannon, E., Kumari, M., Mill, J. and Schalkwyk, L., (2019). . Genome Biology. 20 (1), 283-
Saffari, A., Arno, M., Nasser, E., Ronald, A., Wong, CCY., Schalkwyk, LC., Mill, J., Dudbridge, F. and Meaburn, EL., (2019). . Molecular Autism. 10 (1), 38-38
Rutten, BPF., Vermetten, E., Vinkers, CH., Ursini, G., Daskalakis, NP., Pishva, E., de Nijs, L., Houtepen, LC., Eijssen, L., Jaffe, AE., Kenis, G., Viechtbauer, W., van den Hove, D., Schraut, KG., Lesch, K-P., Kleinman, JE., Hyde, TM., Weinberger, DR., Schalkwyk, L., Lunnon, K., Mill, J., Cohen, H., Yehuda, R., Baker, DG., Maihofer, AX., Nievergelt, CM., Geuze, E. and Boks, MPM., (2018). . Molecular Psychiatry. 23 (5), 1145-1156
Smith, RG., Hannon, E., De Jager, PL., Chibnik, L., Lott, SJ., Condliffe, D., Smith, AR., Haroutunian, V., Troakes, C., Al-Sarraj, S., Bennett, DA., Powell, J., Lovestone, S., Schalkwyk, L., Mill, J. and Lunnon, K., (2018). . Alzheimer's and Dementia. 14 (12), 1580-1588
Hughes, A., Smart, M., Gorrie-Stone, T., Hannon, E., Mill, J., Bao, Y., Burrage, J., Schalkwyk, L. and Kumari, M., (2018). . American Journal of Epidemiology. 187 (11), 2346-2354
Hannon, E., Gorrie-Stone, TJ., Smart, MC., Burrage, J., Hughes, A., Bao, Y., Kumari, M., Schalkwyk, LC. and Mill, J., (2018). . The American Journal of Human Genetics. 103 (5), 654-665
Marzi, SJ., Leung, SK., Ribarska, T., Hannon, E., Smith, AR., Pishva, E., Poschmann, J., Moore, K., Troakes, C., Al-Sarraj, S., Beck, S., Newman, S., Lunnon, K., Schalkwyk, LC. and Mill, J., (2018). . Nature Neuroscience. 21 (11), 1618-1627
O鈥橞rien, HE., Hannon, E., Hill, MJ., Toste, CC., Robertson, MJ., Morgan, JE., McLaughlin, G., Lewis, CM., Schalkwyk, LC., Hall, LS., Pardi帽as, AF., Owen, MJ., O鈥橠onovan, MC., Mill, J. and Bray, NJ., (2018). . Genome Biology. 19 (1), 194-
Viana, J., Hannon, E., Dempster, E., Pidsley, R., Macdonald, R., Knox, O., Spiers, H., Troakes, C., Al-Saraj, S., Turecki, G., Schalkwyk, LC. and Mill, J., (2017). . Human Molecular Genetics. 26 (1), 210-225
Malki, K., Tosto, MG., Mouri帽o鈥怲al铆n, H., Rodr铆guez鈥怢orenzo, S., Pain, O., Jumhaboy, I., Liu, T., Parpas, P., Newman, S., Malykh, A., Carboni, L., Uher, R., McGuffin, P., Schalkwyk, LC., Bryson, K. and Herbster, M., (2017). . American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 174 (3), 235-250
Janecka, M., Marzi, SJ., Parsons, MJ., Liu, L., Paya-Cano, JL., Smith, RG., Fernandes, C. and Schalkwyk, LC., (2017). . Scientific Reports. 7 (1), 41204-
Janecka, M., Mill, J., Basson, MA., Goriely, A., Spiers, H., Reichenberg, A., Schalkwyk, LC. and Fernandes, C., (2017). . Translational Psychiatry. 7 (1), e1019-e1019
Janecka, M., Haworth, CMA., Ronald, A., Krapohl, E., Happ茅, F., Mill, J., Schalkwyk, LC., Fernandes, C., Reichenberg, A. and Rijsdijk, F., (2017). . Journal of the American Academy of Child & Adolescent Psychiatry. 56 (5), 383-390
Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, EB., Devall, M., Soininen, H., K艂oszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, AN., Powell, J., Lovestone, S. and Hodges, A., (2017). . Neurobiology of Aging. 53, 36-47
Devall, M., Smith, RG., Jeffries, A., Hannon, E., Davies, MN., Schalkwyk, L., Mill, J., Weedon, M. and Lunnon, K., (2017). . Clinical Epigenetics. 9 (1), 47-
Spiers, H., Hannon, E., Schalkwyk, LC., Bray, NJ. and Mill, J., (2017). . BMC Genomics. 18 (1), 738-
Smith, AR., Smith, RG., Condliffe, D., Hannon, E., Schalkwyk, L., Mill, J. and Lunnon, K., (2016). . Neurobiology of Aging. 47, 35-40
Hannon, E., Dempster, E., Viana, J., Burrage, J., Smith, AR., Macdonald, R., St Clair, D., Mustard, C., Breen, G., Therman, S., Kaprio, J., Toulopoulou, T., Pol, HEH., Bohlken, MM., Kahn, RS., Nenadic, I., Hultman, CM., Murray, RM., Collier, DA., Bass, N., Gurling, H., McQuillin, A., Schalkwyk, L. and Mill, J., (2016). . Genome Biology. 17 (1), 176-
Lunnon, K., Hannon, E., Smith, RG., Dempster, E., Wong, C., Burrage, J., Troakes, C., Al-Sarraj, S., Kepa, A., Schalkwyk, L. and Mill, J., (2016). . Genome Biology. 17 (1), 27-
Carter, KW., Carter, KW., Francis, RW., Bresnahan, M., Gissler, M., Gr酶nborg, TK., Gross, R., Gunnes, N., Hammond, G., Hornig, M., Hultman, CM., Huttunen, J., Langridge, A., Leonard, H., Newman, S., Parner, ET., Petersson, G., Reichenberg, A., Sandin, S., Schendel, DE., Schalkwyk, L., Sourander, A., Steadman, C., Stoltenberg, C., Suominen, A., Sur茅n, P., Susser, E., Sylvester Vethanayagam, A. and Yusof, Z., (2016). . International Journal of Epidemiology. 45 (2), 408-416
Malki, K., Du Rietz, E., Crusio, WE., Pain, O., Paya鈥怌ano, J., Karadaghi, RL., Sluyter, F., de Boer, SF., Sandnabba, K., Schalkwyk, LC., Asherson, P. and Tosto, MG., (2016). . American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 171 (6), 827-838
Houtepen, LC., Vinkers, CH., Carrillo-Roa, T., Hiemstra, M., Van Lier, PA., Meeus, W., Branje, S., Heim, CM., Nemeroff, CB., Mill, J., Schalkwyk, LC., Creyghton, MP., Kahn, RS., Jo毛ls, M., Binder, EB. and Boks, MPM., (2016). . Nature Communications. 7 (1), creators-Schalkwyk=3ALeonard_C=3A=3A
Hannon, E., Spiers, H., Viana, J., Pidsley, R., Burrage, J., Murphy, TM., Troakes, C., Turecki, G., O'Donovan, MC., Schalkwyk, LC., Bray, NJ. and Mill, J., (2016). . Nature Neuroscience. 19 (1), 48-54
Malki, K., Tosto, MG., Pain, O., Sluyter, F., Mineur, YS., Crusio, WE., de Boer, S., Sandnabba, KN., Kesserwani, J., Robinson, E., Schalkwyk, LC. and Asherson, P., (2016). . American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 171 (3), 427-436
Marzi, SJ., Meaburn, EL., Dempster, EL., Lunnon, K., Paya-Cano, JL., Smith, RG., Volta, M., Troakes, C., Schalkwyk, LC. and Mill, J., (2016). . Epigenetics. 11 (1), 24-35
Hannon, E., Lunnon, K., Schalkwyk, L. and Mill, J., (2015). . Epigenetics. 10 (11), 1024-1032
Elliott, G., Hong, C., Xing, X., Zhou, X., Li, D., Coarfa, C., Bell, RJA., Maire, CL., Ligon, KL., Sigaroudinia, M., Gascard, P., Tlsty, TD., Harris, RA., Schalkwyk, LC., Bilenky, M., Mill, J., Farnham, PJ., Kellis, M., Marra, MA., Milosavljevic, A., Hirst, M., Stormo, GD., Wang, T. and Costello, JF., (2015). . Nature Communications. 6 (1), creators-Schalkwyk=3ALeonard_C=3A=3A
Janecka, M., Manduca, A., Servadio, M., Trezza, V., Smith, R., Mill, J., Schalkwyk, LC., Reichenberg, A. and Fernandes, C., (2015). . Genes, Brain and Behavior. 14 (6), 443-453
Malki, K., Pain, O., Tosto, MG., Du Rietz, E., Carboni, L. and Schalkwyk, LC., (2015). . Translational Psychiatry. 5 (3), e519-e519
Martin, C., Tansey, KE., Schalkwyk, LC. and Powell, TR., (2015). . Biomarkers in Medicine. 9 (2), 169-180
Malki, K., Mineur, YS., Tosto, MG., Campbell, J., Karia, P., Jumabhoy, I., Sluyter, F., Crusio, WE. and Schalkwyk, LC., (2015). . BMC Genomics. 16 (1), 262-
Spiers, H., Hannon, E., Schalkwyk, LC., Smith, R., Wong, CCY., O鈥橠onovan, MC., Bray, NJ. and Mill, J., (2015). . Genome Research. 25 (3), 338-352
Boks, MP., Mierlo, HCV., Rutten, BPF., Radstake, TRDJ., De Witte, L., Geuze, E., Horvath, S., Schalkwyk, LC., Vinkers, CH., Broen, JCA. and Vermetten, E., (2015). . Psychoneuroendocrinology. 51, 506-512
Ilott, NE., Schneider, T., Mill, J., Schalkwyk, L., Brolese, G., Bizarro, L., Stolerman, IP., Dempster, E. and Asherson, P., (2014). . PLoS ONE. 9 (2), creators-Schalkwyk=3ALeonard_C=3A=3A
Condliffe, D., Wong, A., Troakes, C., Proitsi, P., Patel, Y., Chouliaras, L., Fernandes, C., Cooper, J., Lovestone, S., Schalkwyk, L., Mill, J. and Lunnon, K., (2014). . Neurobiology of Aging. 35 (8), 1850-1854
Viana, J., Pidsley, R., Troakes, C., Spiers, H., Wong, CCY., Al-Sarraj, S., Craig, I., Schalkwyk, L. and Mill, J., (2014). . Epigenetics. 9 (4), 587-599
Bell, JT., Loomis, AK., Butcher, LM., Gao, F., Zhang, B., Hyde, CL., Sun, J., Wu, H., Ward, K., Harris, J., Scollen, S., Davies, MN., Schalkwyk, LC., Mill, J., Williams, FMK., Li, N., Deloukas, P., Beck, S., McMahon, SB., Wang, J., John, SL. and Spector, TD., (2014). . Nature Communications. 5 (1), 2978-
Wong, CCY., Meaburn, EL., Ronald, A., Price, TS., Jeffries, AR., Schalkwyk, LC., Plomin, R. and Mill, J., (2014). . Molecular Psychiatry. 19 (4), 495-503
Pidsley, R., Viana, J., Hannon, E., Spiers, H., Troakes, C., Al-saraj, S., Mechawar, N., Turecki, G., Schalkwyk, LC., Bray, NJ. and Mill, J., (2014). . Genome Biology. 15 (10), creators-Schalkwyk=3ALeonard_C=3A=3A
Malki, K., Pain, O., Du Rietz, E., Tosto, MG., Paya-Cano, J., Sandnabba, KN., de Boer, S., Schalkwyk, LC. and Sluyter, F., (2014). . neurogenetics. 15 (4), 255-266
Powell, TR., McGuffin, P., D'Souza, UM., Cohen-Woods, S., Hosang, GM., Martin, C., Matthews, K., Day, RK., Farmer, AE., Tansey, KE. and Schalkwyk, LC., (2014). . PLoS ONE. 9 (3), creators-Schalkwyk=3ALeonard_C=3A=3A
Tarantino, LM. and Schalkwyk, LC., (2014). . Mammalian Genome. 25 (1-2), 1-2
Powell, TR., Powell鈥怱mith, G., Haddley, K., Mcguffin, P., Quinn, J., Schalkwyk, LC., Farmer, AE. and D'Souza, UM., (2014). . International Journal of Methods in Psychiatric Research. 23 (2), 279-288
Malki, K., Keers, R., Tosto, MG., Lourdusamy, A., Carboni, L., Domenici, E., Uher, R., McGuffin, P. and Schalkwyk, LC., (2014). . BMC Medicine. 12 (1), 73-
Smith, RG., Fernandes, C., Kember, R., Schalkwyk, LC., Buxbaum, J., Reichenberg, A. and Mill, J., (2014). . Molecular Autism. 5 (1), creators-Schalkwyk=3ALeonard_C=3A=3A
Lunnon, K., Smith, R., Hannon, E., De Jager, PL., Srivastava, G., Volta, M., Troakes, C., Al-Sarraj, S., Burrage, J., Macdonald, R., Condliffe, D., Harries, LW., Katsel, P., Haroutunian, V., Kaminsky, Z., Joachim, C., Powell, J., Lovestone, S., Bennett, DA., Schalkwyk, LC. and Mill, J., (2014). . Nature Neuroscience. 17 (9), 1164-1170
Punapart, M., Eltermaa, M., Oflijan, J., S眉tt, S., Must, A., K玫ks, S., Schalkwyk, LC., Fernandes, C., Vasar, E., Soomets, U. and Terasmaa, A., (2014). . PPAR Research. 2014, 1-11
De Jager, PL., Srivastava, G., Lunnon, K., Burgess, J., Schalkwyk, LC., Yu, L., Eaton, ML., Keenan, BT., Ernst, J., McCabe, C., Tang, A., Raj, T., Replogle, J., Brodeur, W., Gabriel, S., Chai, HS., Younkin, C., Younkin, SG., Zou, F., Szyf, M., Epstein, CB., Schneider, JA., Bernstein, BE., Meissner, A., Ertekin-Taner, N., Chibnik, LB., Kellis, M., Mill, J. and Bennett, DA., (2014). . Nature Neuroscience. 17 (9), 1156-1163
Davis, OSP., Band, G., Pirinen, M., Haworth, CMA., Meaburn, EL., Kovas, Y., Harlaar, N., Docherty, SJ., Hanscombe, KB., Trzaskowski, M., Curtis, CJC., Strange, A., Freeman, C., Bellenguez, C., Su, Z., Pearson, R., Vukcevic, D., Langford, C., Deloukas, P., Hunt, S., Gray, E., Dronov, S., Potter, SC., Tashakkori-Ghanbaria, A., Edkins, S., Bumpstead, SJ., Blackwell, JM., Bramon, E., Brown, MA., Casas, JP., Corvin, A., Duncanson, A., Jankowski, JAZ., Markus, HS., Mathew, CG., Palmer, CNA., Rautanen, A., Sawcer, SJ., Trembath, RC., Viswanathan, AC., Wood, NW., Barroso, I., Peltonen, L., Dale, PS., Petrill, SA., Schalkwyk, LS., Craig, IW., Lewis, CM., Price, TS., Donnelly, P., Plomin, R. and Spencer, CCA., (2014). . Nature Communications. 5 (1), creators-Schalkwyk=3ALeonard_C=3A=3A
Smith, RG., Reichenberg, A., Kember, RL., Buxbaum, JD., Schalkwyk, LC., Fernandes, C. and Mill, J., (2013). . Molecular Psychiatry. 18 (6), 635-636
Powell, TR., Smith, RG., Hackinger, S., Schalkwyk, LC., Uher, R., McGuffin, P., Mill, J. and Tansey, KE., (2013). . Translational Psychiatry. 3 (9), e300-e300
Powell, TR., Tansey, KE., Breen, G., Farmer, AE., Craig, IW., Uher, R., McGuffin, P., D鈥橲ouza, UM. and Schalkwyk, LC., (2013). . Journal of Psychopharmacology. 27 (7), 609-615
Pidsley, R., Wong, CCY., Volta, M., Lunnon, K., Mill, J. and Schalkwyk, LC., (2013). . BMC Genomics. 14 (1), 293-
Powell, TR., Schalkwyk, LC., Heffernan, AL., Breen, G., Lawrence, T., Price, T., Farmer, AE., Aitchison, KJ., Craig, IW., Danese, A., Lewis, C., McGuffin, P., Uher, R., Tansey, KE. and D'Souza, UM., (2013). . European Neuropsychopharmacology. 23 (9), 1105-1114
Navarrete, K., Pedroso, I., De Jong, S., Stefansson, H., Steinberg, S., Stefansson, K., Ophoff, RA., Schalkwyk, LC. and Collier, DA., (2013). . American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 162 (1), 1-16
Malki, K., Tosto, MG., Jumabhoy, I., Lourdusamy, A., Sluyter, F., Craig, I., Uher, R., McGuffin, P. and Schalkwyk, LC., (2013). . Pharmacogenomics. 14 (16), 1979-1990
Lill, M., K玫ks, S., Soomets, U., Schalkwyk, LC., Fernandes, C., Lutsar, I. and Taba, P., (2013). . Frontiers in Neuroscience. 7 (7), 33-
K玫ks, S., Overall, RW., Ivask, M., Soomets, U., Guha, M., Vasar, E., Fernandes, C. and Schalkwyk, LC., (2013). . Physiological Genomics. 45 (5), 182-190
Kember, RL., Dempster, EL., Lee, THA., Schalkwyk, LC., Mill, J. and Fernandes, C., (2012). . Brain and Behavior. 2 (4), 455-467
Pidsley, R., Fernandes, C., Viana, J., Paya-Cano, JL., Liu, L., Smith, RG., Schalkwyk, LC. and Mill, J., (2012). . Molecular Brain. 5 (1), 42-
Davies, MN., Volta, M., Pidsley, R., Lunnon, K., Dixit, A., Lovestone, S., Coarfa, C., Harris, RA., Milosavljevic, A., Troakes, C., Al-Sarraj, S., Dobson, R., Schalkwyk, LC. and Mill, J., (2012). . Genome Biology. 13 (6), R43-
Jeffries, AR., Perfect, LW., Ledderose, J., Schalkwyk, LC., Bray, NJ., Mill, J. and Price, J., (2012). . Stem Cells. 30 (9), 1938-1947
Parsons, MJ., Grimm, C., Paya-Cano, J., Fernandes, C., Liu, L., Philip, VM., Chesler, EJ., Nietfeld, W., Lehrach, H. and Schalkwyk, LC., (2012). . BMC Genomics. 13 (1), 476-
Keers, R., Pedroso, I., Breen, G., Aitchison, KJ., Nolan, PM., Cichon, S., N枚then, MM., Rietschel, M., Schalkwyk, LC. and Fernandes, C., (2012). . PLoS ONE. 7 (6), creators-Schalkwyk=3ALeonard_C=3A=3A
Malki, K., Lourdusamy, A., Binder, E., Pay谩-Cano, J., Sluyter, F., Craig, I., Keers, R., McGuffin, P., Uher, R. and Schalkwyk, LC., (2012). . Pharmacogenetics and Genomics. 22 (11), 765-776
Malki, K., Campbell, J., Davies, M., Keers, R., Uher, R., Ward, M., Paya鈥怌ano, J., Aitchinson, KJ., Binder, E., Sluyter, F., Kuhn, K., Selzer, S., Craig, I., McGuffin, P. and Schalkwyk, LC., (2012). . PROTEOMICS. 12 (14), 2355-2365
Powell, TR., Fernandes, C. and Schalkwyk, LC., (2012). Depression鈥怰elated Behavioral Tests. Current Protocols in Mouse Biology. 2 (2), 119-127
Dempster, EL., Pidsley, R., Schalkwyk, LC., Owens, S., Georgiades, A., Kane, F., Kalidindi, S., Picchioni, M., Kravariti, E., Toulopoulou, T., Murray, RM. and Mill, J., (2011). . Human Molecular Genetics. 20 (24), 4786-4796
K玫ks, S., Soomets, U., Plaas, M., Terasmaa, A., Noormets, K., Tillmann, V., Vasar, E., Fernandes, C. and Schalkwyk, LC., (2011). . Physiological Genomics. 43 (24), 1351-1358
Binder, E., Malki, K., Paya-Cano, JL., Fernandes, C., Aitchison, KJ., Math茅, AA., Sluyter, F. and Schalkwyk, LC., (2011). . Pharmacogenetics and Genomics. 21 (12), 779-789
Malki, K., Uher, R., Paya-Cano, J., Binder, E., Rietschel, M., Zobel, A., Mors, O., Hauser, J., Henigsberg, N., Jerman, B., Souery, D., Placentino, A., Ng, MY., Cohen-Woods, S., Sluyter, F., Farmer, A., Aitchison, KJ., Craig, IW., Lewis, CM., McGuffin, P. and Schalkwyk, LC., (2011). . Biological Psychiatry. 69 (4), 360-365
Sikk, K., (2011). . Frontiers in Genetics. 2 (AUG), 42-
Kember, RL., Fernandes, C., Tunbridge, EM., Liu, L., Pay谩鈥怌ano, JL., Parsons, MJ. and Schalkwyk, LC., (2010). . Genes, Brain and Behavior. 9 (8), 925-932
Docherty, SJ., Davis, OSP., Kovas, Y., Meaburn, EL., Dale, PS., Petrill, SA., Schalkwyk, LC. and Plomin, R., (2010). . Genes, Brain and Behavior. 9 (2), 234-247
K玫ks, S., Velthut, A., Sarapik, A., Altm盲e, S., Reinmaa, E., Schalkwyk, LC., Fernandes, C., Lad, HV., Soomets, U., Jaakma, 脺. and Salumets, A., (2010). . MHR: Basic science of reproductive medicine. 16 (4), 229-240
Meaburn, EL., Schalkwyk, LC. and Mill, J., (2010). . Epigenetics. 5 (7), 578-582
Davies, MN., Meaburn, EL. and Schalkwyk, LC., (2010). . Briefings in Functional Genomics. 9 (5-6), 385-390
Schalkwyk, LC., Meaburn, EL., Smith, R., Dempster, EL., Jeffries, AR., Davies, MN., Plomin, R. and Mill, J., (2010). . The American Journal of Human Genetics. 86 (2), 196-212
Davis, OSP., Butcher, LM., Docherty, SJ., Meaburn, EL., Curtis, CJC., Simpson, MA., Schalkwyk, LC. and Plomin, R., (2010). . Behavior Genetics. 40 (6), 759-767
Lad, HV., Liu, L., Paya-Cano, JL., Parsons, MJ., Kember, R., Fernandes, C. and Schalkwyk, LC., (2010). . Physiology & Behavior. 99 (3), 301-316
Schosser, A., Pirlo, K., Gaysina, D., Cohen-Woods, S., Schalkwyk, LC., Elkin, A., Korszun, A., Gunasinghe, C., Gray, J., Jones, L., Meaburn, E., Farmer, AE., Craig, IW. and McGuffin, P., (2010). Utility of the pooling approach as applied to whole genome association scans with high-density Affymetrix microarrays. BMC Research Notes. 3 (1), 274-
Ronald, A., Butcher, LM., Docherty, S., Davis, OSP., Schalkwyk, LC., Craig, IW. and Plomin, R., (2010). . Behavior Genetics. 40 (1), 31-45
Ronald, A., Butcher, LM., Docherty, SJ., Davis, OSP., Schalkwyk, LC., Craig, IW. and Plomin, R., (2010). . Behavior Genetics. 40 (1), 48-48
K玫ks, S., Soomets, U., Paya-Cano, JL., Fernandes, C., Luuk, H., Plaas, M., Terasmaa, A., Tillmann, V., Noormets, K., Vasar, E. and Schalkwyk, LC., (2009). . Physiological Genomics. 37 (3), 249-259
Meaburn, EL., Fernandes, C., Craig, IW., Plomin, R. and Schalkwyk, LC., (2009). . Twin Research and Human Genetics. 12 (4), 372-380
Davis, OSP., Plomin, R. and Schalkwyk, LC., (2009). . Bioinformatics. 25 (2), 281-283
Smith, RG., Kember, RL., Mill, J., Fernandes, C., Schalkwyk, LC., Buxbaum, JD. and Reichenberg, A., (2009). . PLoS ONE. 4 (12), e8456-e8456
Kas, MJH., Gelegen, C., Schalkwyk, LC. and Collier, DA., (2009). . American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 150B (3), 309-317
Overall, R., (2009). Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource. Frontiers in Neuroscience. 3 (NOV), 55-
Davies, MN., Lawn, S., Whatley, S., Fernandes, C., Williams, RW. and Schalkwyk, LC., (2009). . Frontiers in Neuroscience. 3 (OCT), 54-
Meaburn, EL., Harlaar, N., Craig, IW., Schalkwyk, LC. and Plomin, R., (2008). . Molecular Psychiatry. 13 (7), 729-740
K玫ks, S., Fernandes, C., Kurrikoff, K., Vasar, E. and Schalkwyk, LC., (2008). . Behavioural Brain Research. 188 (1), 62-70
Parsons, MJ., Grimm, CH., Paya-Cano, JL., Sugden, K., Nietfeld, W., Lehrach, H. and Schalkwyk, LC., (2008). . Mammalian Genome. 19 (7-8), 552-560
Schalkwyk, LC., Fernandes, C., Nash, MW., Kurrikoff, K., Vasar, E. and K玫ks, S., (2007). . Genes, Brain and Behavior. 6 (3), 299-303
Kas, MJH., Fernandes, C., Schalkwyk, LC. and Collier, DA., (2007). . Molecular Psychiatry. 12 (4), 324-330
Lad, HV., Liu, L., Pay谩-Cano, JL., Fernandes, C. and Schalkwyk, LC., (2007). . Mammalian Genome. 18 (6-7), 482-491
Plomin, R. and Schalkwyk, LC., (2007). . Developmental Science. 10 (1), 19-23
Caspi, A., Williams, B., Kim-Cohen, J., Craig, IW., Milne, BJ., Poulton, R., Schalkwyk, LC., Taylor, A., Werts, H. and Moffitt, TE., (2007). . Proceedings of the National Academy of Sciences. 104 (47), 18860-18865
Docherty, SJ., Butcher, LM., Schalkwyk, LC. and Plomin, R., (2007). . BMC Genomics. 8 (1), 214-214
Sugden, K., D'Souza, UM., Aitchison, KJ., Schalkwyk, LC., McGuffin, P., Byers, H., Campbell, J., Hye, A. and Pariante, CM., (2007). . European Neuropsychopharmacology. 17, S27-S28
Fernandes, C., Hoyle, E., Dempster, E., Schalkwyk, LC. and Collier, DA., (2006). . Genes, Brain and Behavior. 5 (6), 433-440
Meaburn, E., Butcher, LM., Schalkwyk, LC. and Plomin, R., (2006). . Nucleic Acids Research. 34 (4), creators-Schalkwyk=3ALeonard_C=3A=3A
D'Souza, U., Sugden, K., Aitchison, KJ., Schalkwyk, LC., McGuffin, P. and Pariante, M., (2006). . European Neuropsychopharmacology. 16, S187-S187
Galsworthy, MJ., Paya-Cano, JL., Liu, L., Monle贸n, S., Gregoryan, G., Fernandes, C., Schalkwyk, LC. and Plomin, R., (2005). . Behavior Genetics. 35 (5), 675-692
Butcher, LM., Meaburn, E., Knight, J., Sham, PC., Schalkwyk, LC., Craig, IW. and Plomin, R., (2005). . Human Molecular Genetics. 14 (10), 1315-1325
Butcher, LM., Meaburn, E., Dale, PS., Sham, P., Schalkwyk, LC., Craig, IW. and Plomin, R., (2005). . Molecular Psychiatry. 10 (4), 384-392
Simpson, CL., Knight, J., Butcher, LM., Hansen, VK., Meaburn, EL., Schalkwyk, LC., Craig, IW., Powell, JF., Sham, PC. and Al-Chalabi, A., (2005). . Nucleic Acids Research. 33 (3), e25-e25
Meaburn, E., Butcher, LM., Liu, L., Fernandes, C., Hansen, V., Al-Chalabi, A., Plomin, R., Craig, I. and Schalkwyk, LC., (2005). . BMC Genomics. 6 (1), creators-Schalkwyk=3ALeonard_C=3A=3A
Butcher, LM., Meaburn, E., Liu, L., Fernandes, C., Hill, L., Al-Chalabi, A., Plomin, R., Schalkwyk, L. and Craig, IW., (2004). . Behavior Genetics. 34 (5), 549-555
Stolerman, IP., Chamberlain, S., Bizarro, L., Fernandes, C. and Schalkwyk, L., (2004). . Neuropharmacology. 46 (3), 363-371
Nyberg, J., Sandnabba, K., Schalkwyk, L. and Sluyter, F., (2004). . Genes, Brain and Behavior. 3 (2), 101-109
Fernandes, C., Liu, L., Paya-Cano, JL., Gregorov锟, SA., Forejt, J. and Schalkwyk, LC., (2004). . Behavior Genetics. 34 (6), 621-630
Fernandes, C., Paya鈥怌ano, JL., Sluyter, F., D'Souza, U., Plomin, R. and Schalkwyk, LC., (2004). . European Journal of Neuroscience. 19 (9), 2576-2582
(2004). . Nature Genetics. 36 (11), 1133-1137
Ben Abdelkhalek, H., Beckers, A., Schuster-Gossler, K., Pavlova, MN., Burkhardt, H., Lickert, H., Rossant, J., Reinhardt, R., Schalkwyk, LC., M眉ller, I., Herrmann, BG., Ceolin, M., Rivera-Pomar, R. and Gossler, A., (2004). . Genes & Development. 18 (14), 1725-1736
Craig, IW., Mill, J., Craig, GM., Loat, C. and Schalkwyk, LC., (2004). . European Journal of Human Genetics. 12 (8), 639-646
Sluyter, F. and Schalkwyk, LC., (2003). . Behavior Genetics. 33 (5), 457-460
(2003). . Nature Reviews Genetics. 4 (11), 911-916
Mill, J., Galsworthy, MJ., Paya鈥怌ano, JL., Sluyter, F., Schalkwyk, LC., Plomin, R. and Asherson, P., (2002). . Genes, Brain and Behavior. 1 (3), 166-173
Klose, J., Nock, C., Herrmann, M., St眉hler, K., Marcus, K., Bl眉ggel, M., Krause, E., Schalkwyk, LC., Rastan, S., Brown, SDM., B眉ssow, K., Himmelbauer, H. and Lehrach, H., (2002). . Nature Genetics. 30 (4), 385-393
Schalkwyk, LC., Cusack, B., Dunkel, I., Hopp, M., Kramer, M., Palczewski, S., Piefke, J., Scheel, S., Weiher, M., Wenske, G., Lehrach, H. and Himmelbauer, H., (2001). . Genome Research. 11 (12), 2142-2150
Ryu, S., Cho, S., Park, S., Lim, W., Kim, M., Hong, S., Bae, D., Park, Y., Kim, B., Kim, H. and Yun, H., (2001). Cloning of the cel 9A gene and characterization of its gene product from marine bacterium Pseudomonas sp. SK38. Applied Microbiology and Biotechnology. 57 (1-2), 138-145
Leong, WL., Dobson, MJ., Logsdon, Jr., JM., Abdel-Majid, RM., Schalkwyk, LC., Guernsey, DL. and Neumann, PE., (2000). . Mammalian Genome. 11 (2), 97-103
G枚sele, C., Hong, L., Kreitler, T., Rossmann, M., Hieke, B., Gro脽, U., Kramer, M., Himmelbauer, H., Bihoreau, M-T., Kwitek-Black, AE., Twigger, S., Tonellato, PJ., Jacob, HJ., Schalkwyk, LC., Lindpaintner, K., Ganten, D., Lehrach, H. and Knoblauch, M., (2000). . Genomics. 69 (3), 287-294
Knoblauch, M., G枚sele, C., Zimdahl, H., Hieke, B., Himmelbauer, H., Schalkwyk, L., Lindpaintner, K., Ganten, D. and Lehrach, H., (2000). . Journal of Experimental Animal Science. 41 (1-2), 35-37
Himmelbauer, H., (2000). Interspersed repetitive sequence (IRS)-PCR for typing of whole genome radiation hybrid panels. Nucleic Acids Research. 28 (2), 7e-7
Zhu, B., Smith, JA., Tracey, SM., Konfortov, BA., Welzel, K., Schalkwyk, LC., Lehrach, H., Kollers, S., Masabanda, J., Buitkamp, J., Fries, R., Williams, JL. and Miller, JR., (1999). . Mammalian Genome. 10 (7), 706-709
Hills, D., Tracey, S., Masabanda, J., Fries, R., Schalkwyk, LC., Lehrach, H., Miller, JR. and Williams, JL., (1999). . Mammalian Genome. 10 (8), 837-838
Nock, C., Gauss, C., Schalkwyk, LC., Klose, J., Lehrach, H. and Himmelbauer, H., (1999). Technology development at the interface of proteome research and genomics: Mapping nonpolymorphic proteins on the physical map of mouse chromosomes. Electrophoresis. 20 (4-5), 1027-1032
Nock, C., Gauss, C., Schalkwyk, LC., Klose, J., Lehrach, H. and Himmelbauer, H., (1999). . Electrophoresis. 20 (4-5), 1027-1032
Schalkwyk, LC., Jung, M., Daser, A., Weiher, M., Walter, J., Himmelbauer, H. and Lehrach, H., (1999). . Genome Research. 9 (9), 878-887
Schalkwyk, LC., Himmelbauer, H. and Lehrach, H., (1999). . Archiv fur Tierzucht. 42 (6 SUPPL.), 67-73
Buitkamp, J., Ewald, D., Schalkwyk, L., Weiher, M., Masabanda, J., Sazanov, A., Lehrach, H. and Fries, R., (1998). . Animal Genetics. 29 (4), 295-301
Priestley, A., (1998). . Nucleic Acids Research. 26 (8), 1965-1973
Schalkwyk, LC., Weiher, M., Kirby, M., Cusack, B., Himmelbauer, H. and Lehrach, H., (1998). . Mammalian Genome. 9 (10), 807-811
Himmelbauer, H., Wedemeyer, N., Haaf, T., Wanker, EE., Schalkwyk, LC. and Lehrach, H., (1998). . Mammalian Genome. 9 (1), 26-31
Himmelbauer, H., Dunkel, I., Otto, GW., Burgtorf, C., Schalkwyk, LC. and Lehrach, H., (1998). . Mammalian Genome. 9 (8), 611-616
Abdel-Majid, RM., Leong, WL., Schalkwyk, LC., Smallman, DS., Wong, ST., Storm, DR., Fine, A., Dobson, MJ., Guernsey, DL. and Neumann, PE., (1998). . Nature Genetics. 19 (3), 289-291
Toye, AA., Schalkwyk, L., Lehrach, H. and Bumstead, N., (1997). . Mammalian Genome. 8 (4), 274-276
Crnogorac-Jurcevic, T., Brown, JR., Lehrach, H. and Schalkwyk, LC., (1997). . Genomics. 41 (2), 177-184
Cai, L., Schalkwyk, LC., Schoeberlein-Stehli, A., Zee, RYL., Smith, A., Haaf, T., Georges, M., Lehrach, H. and Lindpaintner, K., (1997). . Genomics. 39 (3), 385-392
Hunter, KW., Riba, L., Schalkwyk, L., Clark, M., Resenchuk, S., Beeghly, A., Su, J., Tinkov, F., Lee, P., Ramu, E., Lehrach, H. and Housman, D., (1996). . Genome Research. 6 (4), 290-299
McCarthy, L., Hunter, K., Schalkwyk, L., Riba, L., Anson, S., Mott, R., Newell, W., Bruley, C., Bar, I. and Ramu, E., (1995). . Proceedings of the National Academy of Sciences. 92 (12), 5302-5306
Schalkwyk, LC., Francis, F. and Lehrach, H., (1995). Techniques in mammalian genome mapping. Current Opinion in Biotechnology. 6 (1), 37-43
Breen, M., Deakin, L., Macdonald, B., Miller, S., Sibson, R., Tarttelin, E., Avner, P., Bourgade, F., Guenet, JL., Montagutelli, X., Poirier, C., Simon, D., Tailor, D., Bishop, M., Kelly, M., Rysavy, F., Rastan, S., Norris, D., Shepherd, D., Abbott, C., Pilz, A., Hodge, S., Jackson, I., Boyd, Y., Blair, H., Maslen, G., Todd, JA., Reed, PW., Stoye, J., Ashworth, A., McCarthy, L., Cox, R., Schalkwyk, LC., Lehrach, H., Klose, J., Gangadharan, U. and Brown, S., (1994). . Human Molecular Genetics. 3 (4), 621-627
A.Jones, K., M.Black, D., A.Brown, M., L.Griffiths, B., M.Nicolai, H., A.Chambers, J., Bonjardim, M., Xu, C-F., Boyd, M., MeFariane, R., Korn, B., Poustka, A., A.North, M., Schalkwyk, L., Lehrach, H. and Solomon, E., (1994). . Human Molecular Genetics. 3 (11), 1927-1934
Jones, JE., Huckaby, CS., Stafford, MD. and Linnoila, RI., (1994). An MspI RFLP of the human AHR gene.. Human molecular genetics. 3 (11), 2083-
(1994). CORRIGENDUM. Human Molecular Genetics. 3 (5), 852-852
Hoheisel, J., (1993). . Cell. 73 (1), 109-120
Schalkwyk, LC., Charlebois, RL. and Doolittle, WF., (1993). . Canadian Journal of Microbiology. 39 (2), 201-206
Schalkwyk, LC., (1993). Chapter 15 Halobacterial genes and genomes. New Comprehensive Biochemistry. 26 (C), 467-496
Cohen, A., Lam, WL., Charlebois, RL., Doolittle, WF. and Schalkwyk, LC., (1992). . Proceedings of the National Academy of Sciences. 89 (5), 1602-1606
Doolittle, WF., Lam, WL., Schalkwyk, LC., Charlebois, RL., Cline, SW. and Cohen, A., (1992). . Biochemical Society symposium. 58 (58), 73-78
Charlebois, RL., Schalkwyk, LC., Hofman, JD. and Doolittle, WF., (1991). . Journal of Molecular Biology. 222 (3), 509-524
Charlebois, RL., Hofman, JD., Schalkwyk, LC., Lam, WL. and Doolittle, WF., (1989). . Canadian Journal of Microbiology. 35 (1), 21-29
Cline, SW., Schalkwyk, LC. and Doolittle, WF., (1989). . Journal of Bacteriology. 171 (9), 4987-4991
Cline, SW., Lam, WL., Charlebois, RL., Schalkwyk, LC. and Doolittle, WF., (1989). . Canadian Journal of Microbiology. 35 (1), 148-152
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Book chapters (1)
Nock, C., Gauss, C., Schalkwyk, LC., Klose, J., Lehrach, H. and Himmelbauer, H., (1999). Technology development at the interface of proteome research and genomics: Mapping nonpolymorphic proteins on the physical map of mouse chromosomes. In: From Genome to Proteome: Advances in the Practice & Application of Proteomics. Wiley. 447- 452. 9783527301546
Conferences (42)
Mill, J., Hannon, E., Dempster, E., Franklin, A., Burrage, J., Davies, J., Chioza, B., Commin, G., Jeffries, AR., Bamford, RA. and Schalkwyk, L., (2023). W76. CELL-SPECIFIC METHYLOMIC VARIATION IN NEURODEVELOPMENT AND SCHIZOPHRENIA
Hannon, E., Davies, J., Chioza, B., Policicchio, S., Burrage, J., Commin, G., Jeffries, AR., Schalkwyk, L., Dempster, E. and Mill, J., (2022). 89. IDENTIFYING CELL-TYPE-SPECIFIC EPIGENETIC VARIATION IN THE CORTEX ASSOCIATED WITH SCHIZOPHRENIA
Shireby, G., Hannon, E., Commin, G., Burrage, J., Davies, J., Policicchio, S., Schalkwyk, L., Dempster, E. and Mill, J., (2021). TH44. LEVERAGING DNA METHYLATION QUANTITATIVE-TRAIT LOCI TO CHARACTERIZE THE RELATIONSHIP BETWEEN METHYLOMIC VARIATION, GENE EXPRESSION, AND PSYCHIATRIC DISEASE
Asenius, F., Marzi, SJ., Gorrie-Stone, TJ., Brew, A., Panchbaya, Y., Williamson, E., Schalkwyk, L., Rakyan, V. and Williams, DJ., (2020). A lack of DNA methylation covariation between human blood and sperm make it unlikely to mediate intergenerational inheritance of acquired traits
Hannon, E., Dempster, E., Burrage, J., Curtis, C., Gillespie, A., Dempster, D., Gunasinghe, C., Schalkwyk, L., Gaughran, F., Murray, R., Di Forti, M., Collier, D., Breen, G. and Mill, J., (2017). AN EPIGENOME-WIDE ASSOCIATION STUDY OF CLOZAPINE USE IN TREATMENT-RESISTANT SCHIZOPHRENIA
Rutten, B., Vermetten, E., Vinkers, C., Pishva, E., Kenis, G., de Nijs, L., Eijssen, L., Viechtbauer, W., van den Hove, D., Schraut, K., Lesch, K-P., Daskalakis, N., Yehuda, R., Schalkwyk, L., Lunnon, K., Mill, J., Nievergelt, C., Baker, DS., Geuze, E. and Boks, MPM., (2015). Blood-based DNA Methylation Signatures of Susceptibility to Traumatic Stress; Results From A Dutch Prospective Military Cohort Study
Spiers, H., Bray, NJ., Hannon, E., Schalkwyk, LC., Wong, CC., Pidsley, R., Smith, RG. and Mill, J., (2015).
Boks, MPM., van Mierlo, H., Rutten, BPF., Radstake, TRDJ., De Witte, LD., Geuze, E., Horvath, S., Schalkwyk, LC., Vinkers, CH., Broen, JCA. and Vermetten, E., (2015). Longitudinal Changes of Telomere Length and Epigenetic Age Related to Traumatic Stress and Post-traumatic Stress Disorder
Powell, TR., Schalkwyk, LC., Breen, G., Lawrence, T., Pariante, C., McGuffin, P., Tansey, K., Uher, R. and D'Souza, UM., (2012). Identifying transcriptomic biomarkers for response to escitalopram in the inflammatory cytokine pathway
K玫ks, S., Velthut, A., Sarapik, A., Altm盲e, S., Reinmaa, E., Schalkwyk, LC., Fernandes, C., Lad, H., Soomets, U., Jaakma, 脺W. and Salumets, A., (2011). 166 THE DIFFERENTIAL TRANSCRIPTOME AND ONTOLOGY PROFILES OF MURAL AND CUMULUS GRANULOSA CELLS IN STIMULATED HUMAN ANTRAL FOLLICLES
Sikk, K., Koks, S., Soomets, U., Schalkwyk, LC., Fernandes, C., Haldre, S., Aquilonius, S-M. and Taba, P., (2010). Peripheral blood RNA gene expression profiling in illicit methcathinone users reveals effect on immune system
Amos-Landgraf, J. and Schalkwyk, LC., (2008). The 21st International Mammalian Genome Conference Meeting Report
Meaburn, E., Harlaar, N., Craig, IW., Schalkwyk, LC. and Plomin, R., (2007).
Binder, E., Paya-Cano, JL., Sluyter, F. and Schalkwyk, LC., (2006).
Paya-Cano, JL., Sluyter, F., Mineur, YS., Fernandes, C., Crusio, WE. and Schalkwyk, LC., (2006).
Meaburn, E., Butcher, LM., Harlaar, N., Curtis, C., Craig, IW., Schalkwyk, LC. and Plomin, R., (2006).
Huezo-Diaz, P., Williamson, R., Nash, MW., Sim, SC., Alhberg, S., Hoda, F., Rietschel, M., Schmal, C., Farmer, A., Schulze, T., Hauser, J., Henigsberg, N., Maier, W., Zobel, A., Larsen, ER., Mors, O., Mendelewicz, J., Marusic, A., Perez, J., Schalkwyk, L., McGuffin, P., Craig, I., Ingelman-Sundberg, M. and Aitchison, KJ., (2006).
D'Souza, UM., Sugden, K., Pariante, CM., Byers, H., Ward, M., Schalkwyk, LC., McGuffin, P. and Aitchison, KJ., (2006).
Butcher, LM., Meaburn, EL., Craig, IW., Schalkwyk, LC. and Plomin, R., (2006).
D'Souza, UM., Sugden, K., Pariante, CM., Byers, H., Ward, M., Schalkwyk, LC., McGuffin, P. and Aitchison, KJ., (2006). Effects of antidepressant treatment on gene expression in mouse cultured cells
Liu, L., Fernandes, C., Brookes, K., Paya-Capo, J., Asherson, P. and Schalkwyk, LC., (2005).
Meaburn, EL., Butcher, LM., Knight, J., Craig, I., Schalkwyk, LC. and Plomin, R., (2005).
Butcher, LM., Meaburn, E., Knight, J., Sham, PC., Schalkwyk, LC., Craig, IW. and Plomin, R., (2005).
Butcher, LM., Meaburn, E., Knight, J., Sham, PC., Schalkwyk, LC., Craig, IW. and Plomin, R., (2005).
Sugden, K., D'Souza, UM., McGuffin, P., Schalkwyk, LC., Aitchison, KJ. and Pariante, CM., (2005).
Fernandes, C., Liu, L., Paya-Cano, JL., Whatley, SA. and Schalkwyk, LC., (2004).
Meaburn, EL., Butcher, ML., Liu, L., Fernandes, C., Sham, P., Plomin, R., Craig, I. and Schalkwyk, L., (2004).
Chamberlain, S., Bizarro, L., Fernandes, C., Schalkwyk, L. and Stolerman, IP., (2003). Nicotinic receptors containing the alpha7 subunit do not contribute to nicotine discrimination
Sluyter, F. and Schalkwyk, LC., (2003). Symposium: Using microarrays in the analysis of behavior
Fernandes, C., Paya-Cano, J., Sluyter, F., D'Souza, U., Plomin, R. and Schalkwyk, LC., (2003). The power of gene expression profiling and mouse models to unravel behavior.
Meaburn, E., Schalkwyk, L., Criag, I. and Plomin, R., (2003). A genome wide scan using 400 non-synonymous SNP markers in DNA pools identifies genes associated with language impairment in children
Meaburn, EK., Butcher, LM., Schalkwyk, L., Craig, I. and Plomin, R., (2002). Localisation of quantitative trait loci responsible for the heritability of language impairment using DNA pooling
Hill, L., Meaburn, E., Butcher, LM., Schalkwyk, L., Craig, IW. and Plomin, R., (2002). A genome scan using non-synonymous SNPs in coding regions and general cognitive ability
Galsworthy, MJ., Paya-Cano, JL., Liu, L., Fernandes, C., Schalkwyk, L. and Plomin, R., (2002). The reliabilities, interrelationships and quantitative genetics of cognitive tasks in mus musculus: A study of 250 heterogeneous stock mice
Tandon, K., Schalkwyk, L., Patel, M., Kinirons, M., Kerwin, R., McGuffin, P. and Aitchison, KJ., (2002).
Tandon, K., Schalkwyk, LC., Checkley, S., Patel, M., Kinirons, M., Kerwin, RW., McGuffin, P. and Aitchison, KJ., (2002).
Butcher, LM., Meaburn, EL., Hill, L., Plomin, R. and Schalkwyk, L., (2002). How many non-synonymous SNPS are available on public databases?
Tandon, K., Schalkwyk, L., Checkley, S., Patel, M., Kinirons, M., Kerwin, RW., McGuffin, P. and Aitchison, KJ., (2002). CYP2D6 genotype and treatment with tricyclic antidepressants
Meaburn, EL., Plomin, R. and Schalkwyk, L., (2001). Single nucleotide polymorphism genotyping in DNA pools.
Vettakkorumakankav, NN., Stevenson, KJ., Schalkwyk, LC. and Doolittle, WF., (1994). Disruption of the gene coding for dihydrolipoamide dehydrogenase in Haloferax volcanii by homologous recombination.
ROSS, MT., KNIGHTS, CJ., ROEST CROLLIUS, H., LABELLA, T., HOLLOWAY, E., MIFSUD, J., LI, K., LAM, V., VATCHEVA, R., KUMLEIN, J., FRANCIS, F., MOTT, R., SCHALKWYK, L., BHOGAL, R., ZEHETNER, G. and LEHRACH, H., (1993). BUILDING AN INTEGRATED PHYSICAL AND GENETIC-MAP OF THE HUMAN X-CHROMOSOME
DOOLITTLE, WF., CHARLEBOIS, RL., SCHALKWYK, LC., LAM, WL., CONOVER, RK., TSOULUHAS, D., CLINE, SW., HOFMAN, JD. and COHEN, A., (1991).
Reports and Papers (3)
Wang, Y., Gorrie-Stone, TJ., Grant, OA., Andrayas, AD., Zhai, X., McDonald-Maier, KD. and Schalkwyk, LC., (2021). interpolatedXY: a two-step strategy to normalise DNA methylation microarray data avoiding sex bias
Wang, Y., Hannon, E., Grant, OA., Gorrie-Stone, TJ., Kumari, M., Mill, J., Zhai, X., McDonald-Maier, KD. and Schalkwyk, LC., (2020). DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy
Hannon, E., Gorrie-Stone, T., Smart, M., Burrage, J., Hughes, A., Bao, Y., Kumari, M., Schalkwyk, L. and Mill, J., (2018). Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits
Other (15)
Hannon, E., Bray, N., Weedon, M., Gorrie-Stone, T., Smart, M., Kumari, M., Schalkwyk, L., O'Donovan, M. and Mill, J., (2019).PLEIOTROPIC EFFECTS OF GENETIC VARIATION ASSOCIATED WITH PSYCHIATRIC DISORDERS ON DNA METHYLATION. European Neuropsychopharmacology. 29,Elsevier BV
Hannon, E., Dempster, E., Burrage, J., McQuillin, A., Clair, DS., Morris, D., Di Forti, M., Gaughran, F., MacCabe, J., Breen, G., Collier, D., Murray, R., Schalkwyk, L. and Mill, J., (2019).AN INTEGRATED GENETIC-EPIGENETIC ANALYSIS OF SCHIZOPHRENIA: EVIDENCE FOR CO-LOCALIZATION OF GENETIC ASSOCIATIONS AND DIFFERENTIAL DNA METHYLATION FROM A LARGE META-ANALYSIS OF WHOLE BLOOD DNA. European Neuropsychopharmacology. 29,Elsevier BV
Mill, J., Hannon, E., Spiers, H., Wong, CCY., Viana, J., O'Donovan, M., Schalkwyk, L. and Bray, N., (2019).Regulatory Genomic Variation In The Developing Brain: Relevance To Neuropsychiatric Phenotypes. European Neuropsychopharmacology. 29,Elsevier BV
Hannon, E., Marzi, S., Schalkwyk, L. and Mill, J., (2019).F61GENETIC RISK VARIANTS FOR BRAIN DISORDERS ARE SIGNIFICANTLY ENRICHED IN ACTIVE ENHANCERS IN THE CORTEX. European Neuropsychopharmacology. 29,Elsevier BV
Hannon, E., Dempster, E., Mansell, G., Schalkwyk, L., Murray, R., McQuillin, A., Kowalec, K., Clair, DS., Morris, D., Sullivan, P., O'Donovan, M., MacCabe, J., Collier, D. and Mill, J., (2019).57METHYLOMIC BIOMARKERS OF SCHIZOPHRENIA AND ANTIPSYCHOTIC MEDICATION EXPOSURE. European Neuropsychopharmacology. 29,Elsevier BV
O'Brien, H., Hannon, E., Hill, M., Toste, C., Robertson, M., Morgan, J., McLaughlin, G., Lewis, C., Schalkwyk, L., Pardinas, A., Owen, M., O'Donovan, M., Mill, J. and Bray, N., (2019).55EXPRESSION QUANTITATIVE TRAIT LOCI IN THE DEVELOPING HUMAN BRAIN AND THEIR ENRICHMENT IN NEUROPSYCHIATRIC DISORDERS. European Neuropsychopharmacology. 29,Elsevier BV
Richmond, RC., Bao, Y., Smart, M., Gorrie-Stone, T., Schalkwyk, L., Mill, J., Davey Smith, G., Benzeval, M., Relton, C. and Kumari, M., (2018).P8鈥匢nvestigating epigenetic differences in response to shift work: findings fromunderstanding society(UK longitudinal household survey). Poster presentations. 72,BMJ Publishing Group Ltd
Hannon, E., Lunnon, K., Schalkwyk, L. and Mill, J., (2017).CHARACTERIZING INTER-INDIVIDUAL VARIATION IN DNA METHYLATION BETWEEN BLOOD AND BRAIN: IMPLICATIONS FOR EPIGENETIC STUDIES OF PSYCHIATRIC PHENOTYPES. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27
Hannon, E., Spiers, H., Viana, J., Pidsley, R., Burrage, J., Murphy, T., Troakes, C., Turecki, G., O'Donovan, M., Schalkwyk, L., Bray, NJ. and Mill, J., (2017).METHYLATION QUANTITATIVE TRAIT LOCI (MQTL) IN THE DEVELOPING HUMAN BRAIN AND THEIR ENRICHMENT IN GENOMIC REGIONS ASSOCIATED WITH SCHIZOPHRENIA. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27
Viana, J., Pidsley, R., Hannon, E., Spiers, H., Troakes, C., Al-Saraj, S., Mechawar, N., Turecki, G., Schalkwyk, L., Bray, NJ. and Mill, J., (2017).INVESTIGATING EPIGENOMIC REGULATION IN SCHIZOPHRENIA. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27
Xia, B., Kepa, A., Colvert, E., Mea-burn, E., Ronald, A., Schalkwyk, L., Mill, J., Plomin, R., Happe, F. and Wong, CCY., (2017).AN INVESTIGATION OF X-CHROMOSOME INACTIVATION PROFILES USING A GENETICALLY SENSITIVE DISCORDANT TWIN DESIGN. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27
Hannon, E., Dempster, E., Burrage, J., Smith, A., Gurling, H., Basso, N., McQuillin, A., Schalkwyk, L. and Mill, J., (2017).AN INTEGRATED GENETIC-EPIGENETIC ANALYSIS OF SCHIZOPHRENIA. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27
Dempster, E., Hannon, E., Schalkwyk, L., Bohlken, M., Kaprio, J., Toulopoulou, T., Spector, T., Hulshoffpol, H., Nenadic, I., Cannon, T., Hultman, C., Murray, R. and Mill, J., (2017).GENOME-WIDE METHYLOMIC ANALYSIS OF MONOZYGOTIC TWINS DISCORDANT FOR SCHIZOPHRENIA. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27
Wong, CCY., Parikshak, N., Spiers, H., Brays, NJ., Lysenko, L., Troakes, C., Viana, J., Hannon, E., Schalkwyk, L., Geschwind, D. and Mill, J., (2017).METHYLOMIC ANALYSIS OF AUTISM BRAIN: DISEASE ASSOCIATED VARIATION AND SUPPORT FOR A NEURODEVELOPMENTAL COMPONENT TO ETIOLOGY. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27
Spiers, H., Hannon, E., Schalkwyk, L., Bray, N. and Mill, J., (2017).DNA HYDROXYMETHYLATION ASSOCIATED WITH HUMAN FETAL BRAIN DEVELOPMENT. EUROPEAN NEUROPSYCHOPHARMACOLOGY. 27
Grants and funding
2022
Mapping cell-type-specific regulatory genomic variation in Alzheimer's disease pathology.
Medical Research Council
2020
Building an Autism Research Network in Vietnam
糖心Vlog (GCRF)
2017
Regulatory genomic profiling in schizophrenia
Medical Research Council
2014
Methylomic Profiling in Schizophrenia: Towards an Integrated Genetic-Epigenetic Approach
Medical Research Council