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Dr Antonio Marco

Senior Lecturer
School of Life Sciences
Dr Antonio Marco
  • Email

  • Telephone

    +44 (0) 1206 873339

  • Location

    3SW.3.06, Colchester Campus

Profile

Biography

2020-present Senior Lecturer. 糖心Vlog. 2013-2020 Lecturer. 糖心Vlog. 2012-2013 Stepping Stones Research Fellow. University of Manchester. 2009-2012 Research Associate. University of Manchester. 2008-2009 Postdoctoral Research Associate. Arizona State University. 2007-2008 Research Assistant. Universidad de Valencia. 2003-2007 Predoctoral Fellow. Universidad de Valencia. Current Members: Mohab Helmy, PhD student Andrea Hatlen, PostDoc My blog on evolutionary biology and genetics: http://eblogution.wordpress.com My Google Scholar citation profile is available here: http://scholar.google.co.uk/citations?user=vJrDewYAAAAJ My ORCID profile is accesible here: http://orcid.org/0000-0002-8603-7503

Qualifications

  • Ph. D. Genetics (University of Valencia, 2007),

  • B. Sc. Biological Sciences (University of Valencia, 2002),

  • Grad. Dip. Mathematics (LSE University of London, 2017),

Research and professional activities

Research interests

Evolution is driven by changes in the genome, not only in their gene products but in their regulatory interactions. My research interest is in evolutionary genomics with a strong focus on gene regulatory mechanisms.

Current research

Evolutionary dynamics of gene regulatory networks

MicroRNA function and evolution

Regulatory RNAs in Drosophila

Analysis of high-throughput sequencing for gene expression

Teaching and supervision

Current teaching responsibilities

  • Quantitative methods for Life Sciences (BS141)

  • Employability Skills for the Biosciences (BS211)

  • Biomedical Science: Practice and Employability (BS214)

  • Genome Bioinformatics (BS312)

  • Human Molecular Genetics (BS320)

  • Research Project in Life Sciences (BS832)

  • Analysis of Genomic Data (BS939)

  • Advanced Research Skills (BS953)

  • Genomics (BS982)

  • Professional Skills and the Business of Biosciences (BS985)

  • Research Project - Health Genomics (BS996)

  • Research Project in Biomedical Science (BS831)

Previous supervision

Ana-Maria Dumitrana
Ana-Maria Dumitrana
Thesis title: Computational Design of Dnazymes
Degree subject: Cell and Molecular Biology
Degree type: Doctor of Philosophy
Awarded date: 15/5/2023
Anthonia Adejumoke Ekperuoh
Anthonia Adejumoke Ekperuoh
Thesis title: Measuring Protein-Coding Gene Expression From Small Rna Experiments: Applications to Degraded Cancer Samples
Degree subject: Biological Sciences
Degree type: Doctor of Philosophy
Awarded date: 24/4/2023
Jareth Charles Wolfe
Jareth Charles Wolfe
Thesis title: An Explainable Artificial Intelligence Approach for Decoding the Enhancer Histone Modification Code and Identification of Novel Enhancers
Degree subject: Biological Sciences
Degree type: Doctor of Philosophy
Awarded date: 11/4/2022
Alessandra Pisante
Alessandra Pisante
Thesis title: Characterisation of Human Transcription Factors Binding Mechanisms in Human Cell Lines Using a Statistical Thermodynamic Framework.
Degree subject: Biological Sciences
Degree type: Master of Science (by Dissertation)
Awarded date: 10/12/2021
Angela Christine Whipple
Angela Christine Whipple
Thesis title: The Development of Gene Therapy By Way of Dnazymes, and a Computational Tool That Predicts Dnazyme Efficiency.
Degree subject: Cell and Molecular Biology
Degree type: Doctor of Philosophy
Awarded date: 2/2/2021
Mohab Helmy Abdelfattah Mostafa Elbishbishy
Mohab Helmy Abdelfattah Mostafa Elbishbishy
Thesis title: Cell Signalling and Micrornas: Regulation and Evolution
Degree subject: Biological Sciences
Degree type: Doctor of Philosophy
Awarded date: 5/4/2019

Publications

Publications (4)

Cronin, R., Azadova, A., Marco, A., Laissue, PP., Brooke, GN. and Prischi, F., (2024). The p90 Ribosomal S6 Kinases 2 and 4 promote Prostate Cancer cell proliferation in androgen-dependent and independent ways

Azadova, A., Ekperuoh, A., Brooke, GN. and Marco, A., (2024). Analysis of coding gene expression from small RNA sequencing

Akachukwu, AC., Ratcliff, JS. and Marco, A., (2024). Somatic evolution of cancer genes in sex chromosomes

Marco, A., (2021). The chromosomal distribution of sex-biased microRNAs in Drosophila is non-adaptive

Journal articles (33)

Pine, AC., Brooke, GN. and Marco, A., (2023). . NAR Genomics and Bioinformatics. 5 (1), lqac098-

Marco, A., (2022). . Genome Biology and Evolution. 14 (7), evac103-

Hatlen, A. and Marco, A., (2020). . Molecular Biology and Evolution. 37 (12), 3399-3408

Helmy, M., Hatlen, A. and Marco, A., (2019). . Non-Coding RNA. 5 (2), 42-42

Marco, A., (2019). . Molecular Biology and Evolution. 36 (8), 1843-1843

Hatlen, A., Helmy, M. and Marco, A., (2019). . Database. 2019 (1)

Marco, A., (2018). . PLoS ONE. 13 (4), e0195532-e0195532

Clifton, BD., Librado, P., Yeh, S., Solares, E., Real, D., Jayasekera, S., Zhang, W., Shi, M., Park, R., Magie, R., Ma, H., Xia, X., Marco, A., Rozas, J. and Ranz, JM., (2017). . Molecular Biology and Evolution. 34 (1), 51-65

Marco, A., (2015). . G3 Genes|Genomes|Genetics. 5 (10), 2199-2207

Marco, A., (2014). . Open Biology. 4 (4), 140024-140024

Marco, A., (2014). Sex-biased expression of microRNAs in Drosophila melanogaster. Open biology. 4, creators-Marco=3AAntonio=3A=3A

Marco, A., Ninova, M., Ronshaugen, M. and Griffiths-Jones, S., (2013). . Nucleic Acids Research. 41 (16), 7745-7752

Hui, JHL., Marco, A., Hunt, S., Melling, J., Griffiths-Jones, S. and Ronshaugen, M., (2013). . Nucleic Acids Research. 41 (5), 3352-3361

Marco, A., Kozomara, A., Hui, JHL., Emery, AM., Rollinson, D., Griffiths-Jones, S. and Ronshaugen, M., (2013). . PLoS Neglected Tropical Diseases. 7 (9), e2402-e2402

Marco, A., Ninova, M. and Griffiths-Jones, S., (2013). . Biochemical Society Transactions. 41 (4), 850-854

Jones, MK., Marco, A., Kozomara, A., Hui, JHL., Emery, AM., Rollinson, D., Griffiths-Jones, S. and Ronshaugen, M., (2013). Sex-Biased Expression of MicroRNAs in Schistosoma mansoni. PLoS Neglected Tropical Diseases. 7 (9), creators-Marco=3AAntonio=3A=3A

Marco, A., Hooks, K. and Griffiths-Jones, S., (2012). . RNA Biology. 9 (3), 242-248

Marco, A. and Griffiths-Jones, S., (2012). . Bioinformatics. 28 (3), 318-323

Marco, A., (2012). . Briefings in Functional Genomics. 11 (5), 356-365

Marco, A., MacPherson, JI., Ronshaugen, M. and Griffiths-Jones, S., (2012). . Silence. 3 (1), 8-8

Marco, A., MacPherson, JI., Ronshaugen, M. and Griffiths-Jones, S., (2012). MicroRNAs from the same precursor have different targeting properties. Silence. 3 (1), creators-Marco=3AAntonio=3A=3A

Griffiths鈥怞ones, S., Hui, JHL., Marco, A. and Ronshaugen, M., (2011). . EMBO reports. 12 (2), 172-177

Marco, A., Hui, JHL., Ronshaugen, M. and Griffiths-Jones, S., (2010). . Genome Biology and Evolution. 2, 686-696

Marco, A. and Mar铆n, I., (2009). . BMC Systems Biology. 3 (1), 69-

Kumar, S., Suleski, MP., Markov, GJ., Lawrence, S., Marco, A. and Filipski, AJ., (2009). . Genome Research. 19 (9), 1562-1569

Marco, A. and Marin, I., (2009). . Molecular Biology and Evolution. 26 (10), 2167-2170

Marco, A., Konikoff, C., Karr, TL. and Kumar, S., (2009). . Bioinformatics. 25 (19), 2473-2477

Marco, A. and Mar锟絥, I., (2009). Interactome and Gene Ontology provide congruent yet subtly different views of a eukaryotic cell. BMC Systems Biology. 3 (1), creators-Marco=3AAntonio=3A=3A

Marco, A. and Mar铆n, I., (2008). . BMC Genomics. 9 (1), 219-219

Marco, A. and Mar锟絥, I., (2008). How Athila retrotransposons survive in the Arabidopsis genome. BMC Genomics. 9 (1), creators-Marco=3AAntonio=3A=3A

Marco, A. and Mar铆n, I., (2007). . BMC Bioinformatics. 8 (1), 442-

Marco, A. and Mar锟絥, I., (2007). A general strategy to determine the congruence between a hierarchical and a non-hierarchical classification. BMC Bioinformatics. 8 (1), creators-Marco=3AAntonio=3A=3A

Marco, A., (2004). . Molecular Biology and Evolution. 21 (1), 176-187

Book chapters (2)

Marco, A., (2017). . In: Zygotic Genome Activation. Editors: Lee, K., . Springer. 1- 10. 9781493969869

Marco, A., (2017). . In: Oocytes. Editors: Kloc, M., . Springer. 483- 494. 978-3-319-60854-9

Reports and Papers (5)

Hatlen, A., Helmy, M. and Marco, A., (2019). PopTargs: A database for studying population evolutionary genetics of human microRNA target sites

Helmy, M., Hatlen, A. and Marco, A., (2019). The impact of population variation in the analysis of microRNA target sites

Marco, A., (2018). No evidence of functional co-adaptation between clustered microRNAs

Hatlen, A. and Marco, A., (2018). Pervasive selection against microRNA target sites in human populations

Marco, A., (2017). SeedVicious: analysis of microRNA target and near-target sites

Grants and funding

2024

Summer Studentship 2024 (Liam Burns)

Genetics Society

2022

Identifying Black Men at Increased Risk of Developing Prostate Cancer

Prostate Cancer Research (PCR)

2016

Population dynamics of microRNA regulation: biomedical applications

Wellcome Trust

Contact

amarco@essex.ac.uk
+44 (0) 1206 873339

Location:

3SW.3.06, Colchester Campus

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